Specialized benign form of testicular cyst with keratinizing squamous lining without skin adnexal structures (epidermoid cyst)

Specialized benign form of monodermal cystic teratoma with keratinizing squamous lining and skin adnexal structures (dermoid cyst)

< 1% of testicular tumors

Dermoid cyst more rare than epidermoid cyst

Painless testicular enlargement over several years

Cured by surgical resection

Unilocular intraparenchymal cystic lesion containing keratin debris

Epidermoid cyst: Unilocular cyst with keratinized squamous epithelial lining containing granular cell layer, no skin adnexal structures

Dermoid cyst: Usually unilocular cyst lined by epidermis and dermis containing skin adnexal structures (hair follicle, sebaceous, apocrine or eccrine glands)

Other noncutaneous elements (such as ciliated epithelium, small bowel mucosa and submucosa) may be seen but maintain organoid arrangement

Lipogranulomatous reaction to cyst contents may be seen

Uninvolved testis has normal spermatogenesis with no significant atrophy or “dysgenetic features”