• Triad of symptoms: dysmenorrhea, dyspareunia, infertility. • Physical examination: reveals one or more of the following: tenderness of the pelvic area and/or cul-de-sac, enlarged or tender ovaries, a uterus that tips backward and lacks mobility, fixed pelvic structures, adhesions. • Pelvic ultrasounds: detection and consistency of endome-triomas. • Definitive diagnosis: laparoscopy or laparotomy visualizing pelvic endometrial implants. • Symptoms begin at onset of menstruation or later, worsening with time. Triad of symptoms: dysmenorrhea, dyspareunia, infertility. Features include acute pain before menses, lasting a day or two during menses or throughout the month; vomiting; diarrhea; fainting concurrent with pelvic/abdominal cramping and labor-like pains; chronic bearing down pain; pressure on low back; pains radiating down legs; pain with urination or bowel movements; bleeding from nose, bladder, or bowels; fatigue. • Curious feature: pain and extent of disease correlate poorly. Symptom severity correlates with depth of lesions rather than number of lesions. • Physical examination: one or more of the following: tenderness in pelvic area and/or cul-de-sac; enlarged or tender ovaries; uterus tips backward and lacks mobility; fixed pelvic structure; adhesions. Other findings include endometrial tissue or surgical scar tissue in vagina or on cervix. Examination during the first or second day of menses: tender septum between rectum and vagina. • Pelvic ultrasound: useful assessing pain and tumors but not definitive; detects mass on ovary; determines size, characteristics, consistency of endometriosis. Blood test CA-125 can be positive in endometriosis but cannot distinguish endometriosis, fibroids, malignancies, and even normal tissue. • Definitive diagnosis: biopsy by laparoscopy or laparotomy of visualized tissue. • Estrogens stimulate growth of implants: therapy manipulating endogenous hormones may be effective. • High-fiber foods optimize intestinal transit time and balance friendly gut microflora that displace undesirable strains that deconjugate estrogens, allowing them to recirculate. Less protein, high-fiber organic vegetarian diet: decreases plasma active unconjugated estrogens; reduce intake of proinflammatory arachidonic acid. Vegetable protein, soy, nut butters (almond), salmon are preferred. Emphasize phase 2 liver support vegetables: carrots, beets, artichokes, lemons, dandelion greens, watercress, bur-dock root, cabbage family vegetables. Indole-3-carbinol, in broccoli, Brussels sprouts, cabbage, cauliflower, favors less-active estrogen metabolites. Onions, garlic, and leeks contain immunity-enhancing organosulfur compounds and bioflavonoids (quercetin) that protect against oxidation, block inflammation, and inhibit tumor growth. • Phytoestrogens: soy isoflavones and flaxseed lignans help alleviate endometriosis symptoms. • Seasonings: Turmeric (curcumin) protects against environmental carcinogens, decreases inflammation, increases bile secretion. Milk thistle seeds soaked and ground helps liver function. Fresh flaxseeds increase antiinflammatory fatty acids. Fucus (seaweed) stimulates T-cell production and absorbs toxins.
Endometriosis
DIAGNOSTIC SUMMARY
Diagnostic Considerations
Therapeutic Considerations
Diet
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