Becker U, Gronbaek M, Johansen D, Sorensen TI. Lower risk for alcohol-induced cirrhosis in wine drinkers. Hepatology (Baltimore, Md). 2002;35(4):868–75. doi:10.1053/jhep.2002.32101. Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini…
Fig. 7.1 Potential effects of Wolfberry on the prevention of AD. The development of AD is affected by various risk factors, which can increase the level of oxidative stress, neuroinflammation…
Effect Mechanism Tumors Decrease Oncogene Gastric cancer, pancreatic cancer Apoptosis Liver cancer Expression of several cancer-associated proteins Liver cancer, gastric cancer, colorectal cancer Growth of cancer cells Gastric cancer, colorectal…
USAN: Sitagliptin Phosphate Brand Name: Januvia (Merck) Molecular Weight: 523.32 (Parent, 407.31) FDA Approval: 2006 Drug Class: Dipeptidyl peptidase-4 (DPP-4) inhibitor Indications: Type II Diabetes Mechanism of Action: Competitive and…
USAN: Sofosbuvir Brand Name: Sovaldi (Gilead) Molecular Weight: 529.46 FDA Approval: 2013 Drug Class: Phosphoramide Prodrug of Antiviral Nucelotide Indications: Hepatitis C Virus (HCV) Infection Mechanism of Action: HCV NS5B…
USAN: Imatinib Mesylate Brand Name: Gleevec (Novartis) Molecular Weight: 589.71 (Parent, 493.60) FDA Approval: 2001 Drug Class: Protein-tyrosine Kinase Inhibitor Indications: Treatment of Chronic Myeloid Leukemia (CML) and Gastrointestinal Stromal…
USAN: Esomeprazole Brand Name: Nexium (AstraZeneca) Molecular Weight: 713.13 FDA Approval: 2001 Drug Class: Anti-Ulcer Indications: Gastroesophageal Reflux Disease (GERD) Mechanism of Action: Proton Pump Inhibitor (H+/K+-ATPase Inhibitor) ■ 1…
USAN: Clopidogrel Bisulfate Brand Name: Plavix (Sanofi-Aventis/Bristol-Myers Squibb) Molecular Weight: 419.90 (Parent 321.06) FDA Approval: 1993 Drug Class: Anti-Platelet Indications: Antithrombotic, Blood Thinner Mechanism of Action: Antagonist of the P2Y12…
USAN: Paclitaxel Brand Name: Taxol (Bristol-Myers Squibb) Molecular Weight: 839.92 FDA Approval: 1992 Drug Class: Anticancer Indications: Ovarian, Breast, and Non–Small-Cell Lung Cancer; Kaposi’s Sarcoma Mechanism of Action: Microtubule-stabilizing Agent…
USAN: Duloxetine Hydrochloride Brand Name: Cymbalta (Eli Lilly) Molecular Weight: 277.41 (Parent, 333.88) FDA Approval: 1994 Drug Class: Selective Serotonin and Norepinephrine Reuptake Inhibitor (SNRI) Antidepressant Indications: Major Depressive Disorder,…
