4 – Clinical Sciences
Area 4 – Clinical Sciences Evidence-Based Practice Pharmacist roles Pharmacists have had ever-expanding important roles in healthcare. These include: 1) Maintaining a leadership position in medicine safety and efficiency…
PHARMACY
3 – Social/Behavioral/Administrative Sciences
Important terms Maximum Allowable Costs (MAC) —maximum cost for a specific drug or other product paid for by a patient to a pharmacy. Actual Acquisition Cost (AAC) —the…
Nutritional Supplements
Nutritional Supplements NAME: L-arginine Common Names: Arginine Description and Source: Semi-essential amino acid Biologic Activity Substrate necessary for nitric oxide synthesis and maintenance of activity Nitric oxide acts as a…
An Introduction to Herbal Medicine
An Introduction to Herbal Medicine David Winston RH (AHG) Herbs: Panaceas or Poisons? Certain herbs have become popular during the past 25 years, but herbal medicine is still poorly understood…
Monitoring of Plasma Concentrations of Psychotropic Drugs in Pharmacovigilance
Fig. 6.1 Dose-dependent plasma concentrations of amisulpride in 179 schizophrenic patients treated and observed under everyday conditions. Drug concentrations are highly variable. Under recommended doses of 400–800 mg/day, many patients…
Safety and Tolerability of Medications for ADHD
ADE AMP (%) (5; 1,226)a MPH (%) (16; 2,092)a ATX (%) (21; 3,127)a GUA (%) (6; 1,150)a CLO (%) (1; 154)a Irritability 7–82 1–80 2–12 6–7 8 Crying 76 2–71…
Contribution of UK Prescription-Based Event Monitoring Methods in the Pharmacovigilance of Psychotropic Medications
Study Characteristics PEM M-PEM SCEM Setting Primary care Secondary care Prescribers General Practitioner Specialist Design Non-interventional observational cohort Data Source Secondary use of data from existing medical records Ethics Waiver…
The Role of Pharmacogenetics in Pharmacovigilance of Psychotropic Drugs
Gene Polymorphism(s) Drug/drug class Type of ADR Comment on evidence HLA–B HLA-B*1502 Carbamazepine Stevens-Johnson syndrome Recommended in Asian ancestry CYP2D6 Partially or totally inactive alleles Pimozide Arrhythmia Recommended for doses…
Safety of Psychotropic Drugs in Pregnancy and Breastfeeding
Light gray: Generally considered safe, but uncertainties may exist, e.g., for some of the drugs within a group or related to the total amount of data available Medium gray: Increased…
Safety of Psychotropic Drugs in the Elderly
© Springer International Publishing Switzerland 2016Edoardo Spina and Gianluca Trifirò (eds.)Pharmacovigilance in Psychiatry10.1007/978-3-319-24741-0_14 14. Safety of Psychotropic Drugs in the Elderly Kate L. Lapane1 , Anne Hume2, 3 , Christine Ulbricht1 and Giovanni Gambassi4 (1) Department of Quantitative Health Sciences, Division of…
