Adult Ocular Lesions External Lesions Malignant Melanoma of the Conjunctiva Clinical Features † Deceased • Usually pigmented (may be amelanotic), nodular, elevated lesion with vascularity, anywhere on conjunctiva • Usually…

Osteoid Tumors Osteoma Clinical Features • Male predominance (2:1 to 3:1) • Age ranges from second decade to elderly, with most cases occurring in fourth and fifth decades • Occurs…

Non-Neoplastic Diseases Involving the Splenic White Pulp Reactive Follicular Hyperplasia With Germinal Center Formation Clinical Features • Occurs at any age; more common in children and younger adults • Caused…

Heart Cardiomyopathy Clinical Features Hypertrophic Cardiomyopathy • Myocardial disease characterized by left ventricular hypertrophy in the absence of systemic hypertension, aortic valve stenosis, or overt infiltrative diseases • Associated with…

Non-Neoplastic Conditions Congenital Pulmonary Airway Malformation Clinical Features • Uncommon developmental anomaly predominantly seen in infants that has features of both immaturity and malformation of the airways and distal lung…

Ureter Ureteritis Cystica Et Glandularis Clinical Features • One of the most common non-neoplastic urothelial proliferations • Reactive urothelial proliferation that develops following an inflammatory stimulus • Typically asymptomatic and…

Prostate Gland Acute and Chronic Prostatitis Clinical Features Clinical classification of acute and chronic prostatitis • Acute bacterial prostatitis • Chronic bacterial prostatitis • Chronic abacterial prostatitis • Prostate is…

Nonneoplastic Entities Chronic Pancreatitis Clinical Features • Defined by irreversible loss of pancreatic parenchyma and function caused by inflammation • Patients present with recurrent attacks of abdominal and back pain…

Adrenal Cortical Insufficiency (Addison Disease) Clinical Features Primary Adrenal Cortical Insufficiency Etiology • Autoimmune etiology in 75% to 90% of cases, with circulating autoantibodies to endocrine antigens (21-OH, P-450scc, and…

Light Microscopy Tissue Processing Overview • Fixation • Preserves tissues in situ as close to the lifelike state as possible • Ideally, fixation will be carried out as soon as…