Mediastinal Germ Cell Tumors
Mediastinal germ cell tumor Frequency (% cases) Teratoma 43–75 Seminoma 10–37 Yolk sac tumor 2–12 Embryonal carcinoma 2–8 Choriocarcinoma 2 Mature mediastinal teratomas have been described in patients between 1…
PATHOLOGY & LABORATORY MEDICINE
The Epidemiology of Malignant Germ Cell Tumors: The EUROCARE Study
Proportion of population covered by cancer registries included in EUROCARE-5 (%)a Number of germ cell tumor cases registered in 2000–2007 Austria 100 2.610 Belgium (Flanders) 58 1.215 Bulgaria 100…
Germ Cell Tumors of Miscellaneous Extragonadal Sites
Fig. 11.1 Fetal type adenocarcinoma of the lung. Branching tubules lined by cylindrical epithelium with prominent vacuolation displaying morular aggregates with cells exhibiting optically clear nuclei 11.3 Stomach Gastric teratomas…
Central Nervous System Germ Cell Tumors
Germinoma Embryonal carcinoma Yolk sac tumor Choriocarcinoma Teratoma Immature Mature With malignant transformation Mixed germ cell Other proposed classification systems separate histologic variants into different therapeutic groups based on their…
Somatic-Type Malignancy in Germ Cell Tumors
Type I GCT Type II GCT Type III GCT Type IV GCT Frequency Rare Uncommon Rare Common Location Testis Ovary Extragonadal Testis Ovary Extragonadal Testis Ovary Preexisting GCT Prepubertal…
Pediatric Germ Cell Tumors
Age group Anatomical site Usual histologic type Comments Newborn/infancy Sacrococcygeal (40 %) Ovary mediastinal > abdominal (15–20 % vs. 5 %) Cervicofacial (rare <5 %) Teratoma GCT are the most…
Germ Cell Tumors: Classifications, Definitions, and Terminology
Fig. 1.1 The relative incidence of testicular tumors in the study of Friedman and Moore [11] (Reproduced with permission of the publisher) Fig. 1.2 Schematic drawing illustrating the developmental potential…
Management of Germ Cell Tumors
Taken from the American Cancer Society Website: http://www.cancer.org/cancer/testicularcancer/detailedguide/testicular-cancer-staging The TNM staging system A staging system is a standard way for your cancer care team to sum up the extent of…
Thymic Epithelial Tumors and Benign Thymic Lesions
Relative frequencya Age (y) range (average) Gender (male:female) Myasthenia Gravis (+)b range (mean) Masaoka stage I (%) II (%) III (%) IVa (%) IVb (%) Type A 11.5% (3.1–26.2)…
Cytologic Features of Mediastinal Lesions
Prevascular Mediastinum – Metastatic carcinoma – Thymoma and thymic carcinoma – Germ Cell Tumor – Lymphoma – Thymic cyst – Pericardial cyst – Thymic hyperplasia Visceral Mediastinum – Metastatic carcinoma…
