Age Location Clinical presentation Gross Microscopic features Ancillary tests Fibroepithelial stromal polyp Reproductive age Vulvovaginal region Single mass Flesh-colored mass covered with skin Fibrous tissue and blood vessels Positive…
Criteria • Size > 5 cm • ≥ 5 mitotic figures per 10 high-power fields • Infiltrative edges • Moderate or severe cytologic atypia • Coagulative necrosisa Number of criteria met Diagnosis 0–1b Leiomyoma 2…
Fig. 6.1 Herpes viral simplex infection. Clinically, it presents as multiple grouped vesicles with an erythematous base Originally, HSV shedding was thought to be infrequent given the low rate of…
Type of vulvar SCC HPV-positive SCC HPV-negative SCC Age 35–65 years 55–85 years Risk factors Anogenital warts Lichen sclerosus Smoking Alcohol use Focality Multifocal Single focus Associated VIN Usual (warty/basaloid)…
Fig. 7.1 Vulvar melanosis. An asymmetric, poorly circumscribed, variegated patch mimicking melanoma is evident (left panel). Histopathologically, vulvar (genital) melanosis exhibits, in most cases, increased melanization of the basal keratinocytes,…
Dilatation of preexisting vessels Acquired lymphangiectasis Vulvar varices (venous lake) Angiokeratoma Vascular hyperplasias Pyogenic granuloma (lobular capillary hemangioma) Intravascular papillary endothelial hyperplasia (Masson’s tumor) Benign neoplasms Hemangioma Infantile hemangioma Congenital…
Fig. 11.1 Fibroadenoma. A biphasic tumor comprised of branching glandular structures within a fibrous stroma (Courtesy of Dr. Payal Kapur, Department of Pathology, University of Texas Southwestern Medical Center, Dallas,…
Subcorneal blister Staphylococcal scalded skin syndrome A microbial pustulosis of the folds (Chap. 3) Pemphigus foliaceus Intraepidermal blister Pemphigus vulgaris Papular acantholytic dyskeratosis of vulvocrural area Hailey–Hailey disease Darier’s disease…
Fig. 1.1 External genitalia of the vulva (Used with permission from Robboy et al. [22] Fig. 1.2 Perineal surface anatomy Embryology of the Female Reproductive Tract and External Genitalia The…
Fig. 8.1 Clinical vulvar melanomas present often as large lesions, with variegate pigmentation and irregular borders. Multifocality is not uncommon in vulvar melanomas Dermoscopy Dermoscopy may be used as a…
