(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsThymomaThymic carcinomaTeratomaGerm cell tumorLymphomaBronchogenic cyst The thymus is a lymphoepithelial organ in the anterior mediastinum and is the…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsSertoliLeydigSeminomaSpermatocyticYolk sacEmbryonalTeratomaChoriocarcinoma The testis is not a common specimen. Resections in children or young adults may be…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsUrotheliumTransitionalVon Brunn’s nestPapillaryCarcinoma in situPapillomaNephrogenic adenoma Bladder biopsy specimens are usually submitted to rule out a urothelial…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsSquamousUrotheliumHyperplasiaMetaplasiaDysplasiaCarcinoma in situInvasion Complex, or multilayered, epithelia (squamous and urothelial) may progress through a spectrum of changes,…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsCellularityArchitectureNucleusCytoplasmNecrosisAdjectives The ability to speak the language is essential to effective learning in pathology. This chapter covers…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsBarrett’sGoblet cellsIntestinal metaplasiaDysplasiaEsophagitis The esophagus is composed of a nonkeratinized squamous epithelium overlying a thin lamina propria…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsCytokeratinMelanomaCarcinomaSarcomaLymphomaMesotheliomaGerm cell tumorVascularNeuralMyoepithelial The use of immunostains is a highly complex field in and of itself and…

Location Neuroendocrine cell type (secreted product) Corresponding neoplasm Cytokeratin expression Intestine and appendix EC cell (serotonin); D, L cells; others WD-NET Positive Gastric fundus ECL cell (histamine) WD-NET Positive Gastric…

(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA   KeywordsMicroscopeErgonomicsKöhlerParfocalCondenserObjectiveEyeglasses Using the Microscope Upon arriving in the pathology department, you will most likely be given a…