Malignant Melanoma, Adrenal Glands
Malignant Melanoma, Adrenal Glands Artur Rangel Filho, MD, PhD Vania Nosé, MD, PhD Key Facts Terminology Primary malignant neoplasm of adrenal gland Clinical Issues About 20 cases reported Adrenalectomy and…
PATHOLOGY & LABORATORY MEDICINE
Hyperplasia of Adrenal Medulla and Extraadrenal Paraganglia
Hyperplasia of Adrenal Medulla and Extraadrenal Paraganglia Arthur S. Tischler, MD Key Facts Etiology/Pathogenesis AMH is common in multiple endocrine neoplasia 2A and 2B; absent or very rare in other…
Protocol for the Examination of Specimens From Patients With Carcinoma of the Thyroid Gland
Protocol for the Examination of Specimens From Patients With Carcinoma of the Thyroid Gland Image Gallery Anatomic and Tumor Staging Graphics (Left) Coronal posterior graphic demonstrates the anatomic position of…
Smooth Muscle Tumors
Smooth Muscle Tumors Gene Landon, MD Key Facts Clinical Issues Mostly in pelvis and retroperitoneum of middle-aged/elderly individuals Cytopathology Low-grade leiomyosarcoma (LMS): Plump spindle cells with cigar-shaped nuclei and fibrillar/finely…
Metastatic Tumors
Metastatic Tumors Dina R. Mody, MD Key Facts Clinical Issues Most common primary sites are lung, breast, prostate, kidney, and thyroid Predilection for regions containing red marrow Commonly involved bones…
Giant Cell Tumor
Giant Cell Tumor Dina R. Mody, MD Key Facts Cytopathology Cellular aspirates that may be bloody Dispersed or checkerboard pattern of giant cells and uninucleate stromal cells, which may be…
Solid Pseudopapillary Neoplasm
Solid Pseudopapillary Neoplasm Gene Landon, MD Key Facts Clinical Issues Typically in young females, in body/tail of pancreas Cytopathology Pseudopapillae with tumor cell layer(s) arranged around capillaries ± metachromatic myxoid…
Urothelial Carcinoma
Urothelial Carcinoma Yimin Ge, MD Key Facts Clinical Issues 5-10% of renal tumors, 90% of pelvicalyceal tumors Mean age: 67-70 years, M:F = 1.7-2:1 Cytopathology Hypercellular aspirate Multilayered sheets, papillae,…
Renal Lymphomas
Renal Lymphomas Yimin Ge, MD Jun Zhang, MD, MS Key Facts Clinical Issues PRL accounts for 0.7% of all extranodal lymphomas, including Hodgkin and non-Hodgkin lymphomas SRL is 30x more…
Renal Medullary Carcinoma
Renal Medullary Carcinoma Yimin Ge, MD Key Facts Terminology Rapidly growing medullary tumor associated almost exclusively with sickle cell trait Clinical Issues Predominantly young black males Very aggressive; mean survival:…
