Solitary Rectal Ulcer Syndrome/Mucosal Prolapse Julianne K. Purdy, MD Key Facts Clinical Issues Rare; usually in young to middle-aged adults Ulcer, polyp, erythema on anterior rectal wall Rectal bleeding or…
Lymphocytic Colitis Julianne K. Purdy, MD Key Facts Clinical Issues Middle-aged to elderly individuals Less pronounced female predominance than in collagenous colitis (CC); M:F = 1:1-5.7 Chronic nonbloody diarrhea More…
Mastocytosis Sharon K. Bihlmeyer, MD Key Facts Terminology Systemic mastocytosis involves multiple organs (usually bone marrow) ± skin Clinical Issues Abdominal pain and diarrhea Systemic and gastrointestinal symptoms secondary to…
Collagenous Colitis Julianne K. Purdy, MD Key Facts Clinical Issues Middle-aged to elderly women Chronic nonbloody diarrhea Normal colonoscopy Microscopic Pathology Patchy subepithelial increased collagen Most reliable biopsies from transverse…
Ulcerative Colitis, Colon Scott R. Owens, MD Key Facts Terminology Chronic, idiopathic, remitting, and relapsing inflammatory disease Part of spectrum of inflammatory bowel disease (IBD) Clinical Issues Rectum usually involved…
Melanosis Coli Sharon K. Bihlmeyer, MD Key Facts Terminology Presence of melanin-like pigment in intestinal mucosa Etiology/Pathogenesis Close association with anthraquinone drugs including cascara sagrada, aloe, rhubarb, senna, and frangula…
Preparation Artifacts Julianne K. Purdy, MD Key Facts Clinical Issues Colonic mucosal changes resolve within 2 weeks Macroscopic Features Small aphthoid lesions with pale center and erythematous halo Mainly in…
Endometriosis Sharon K. Bihlmeyer, MD Key Facts Terminology Diagnosis requires 2 of 3 findings Glands, stroma, or hemorrhage Etiology/Pathogenesis Unopposed estrogen therapy increased risk of malignancy in endometriosis Clinical Issues…
Diverticular Disease Sharon K. Bihlmeyer, MD Key Facts Terminology Outpouching from tubular structure True diverticula involve all layers False diverticula when outpouching only involves some of layers (mucosa and submucosa)…
Motility Disorders Scott R. Owens, MD Key Facts Macroscopic Features Sampling of both dilated and normal-appearing areas important Affected organ(s) may be massively dilated Megacolon, megaesophagus, megajejunum, etc. Mucosal stercoral…
