Meninges: Diagnosis
Meninges: Diagnosis Meningiomas arise from the cranial dura and derive their blood supply from it. The underlying brain is compressed . Hyperostosis of adjacent cranial bone is a common feature….
PATHOLOGY & LABORATORY MEDICINE
Hepatic Glomerulosclerosis
Hepatic Glomerulosclerosis Robert B. Colvin, MD Key Facts Terminology Glomerular disease caused by portal hypertension Clinical Issues Present in ˜ 60% of cirrhotics Asymptomatic hematuria, proteinuria Remission with correction of…
Pancreas Resection: Parenchymal, Retroperitoneal, and Bile Duct Margins
Pancreas Resection: Parenchymal, Retroperitoneal, and Bile Duct Margins Tumors of the head of the pancreas are resected with the distal stomach and proximal duodenum . The pancreatic parenchymal margin and…
Pamidronate-induced Collapsing FSGS
Pamidronate-induced Collapsing FSGS A. Brad Farris, III, MD Key Facts Terminology Collapsing FSGS secondary to use of pamidronate, a bisphosphonate inhibitor of bone resorption Clinical Issues HIV-negative patients with nephrotic…
Introduction to Diseases with Monoclonal Immunoglobulin Deposits
Introduction to Diseases with Monoclonal Immunoglobulin Deposits Robert B. Colvin, MD Diagnosis of diseases with monoclonal immunoglobulin deposits &/or substructure by EM is facilitated by following the path in this…
Kidney, Pediatric: Indications and Utility
Kidney, Pediatric: Indications and Utility Wilms tumor is the most common pediatric renal tumor, seen here on CT as a partially enhancing mass within the kidney . A tumor thrombus…
Graft-vs.-Host Glomerulopathies
Graft-vs.-Host Glomerulopathies Anthony Chang, MD Key Facts Terminology Graft-vs.-host disease (GVHD) glomerulopathy Glomerular injury in setting of hematopoietic cell transplantation and GVHD Clinical Issues Proteinuria, nephrotic range Microscopic Pathology 3…
Drug-induced Minimal Change Disease
Drug-induced Minimal Change Disease Anthony Chang, MD Key Facts Etiology/Pathogenesis Common offending agents Nonsteroidal anti-inflammatory drugs (NSAIDs) Cyclooxygenase 2 inhibitors Pamidronate Interferon-α and interferon-β Rifampin Clinical Issues Nephrotic syndrome Treatment…
Lymph Nodes, Axillary: Diagnosis
Lymph Nodes, Axillary: Diagnosis Afferent lymphatics enter the node in a central plane. Bisecting the node in this plane is most likely to reveal metastasis. Macrometastases should be detectable regardless…
Liver: Evaluation of Allograft Prior to Transplantation
Liver: Evaluation of Allograft Prior to Transplantation Each component of the liver parenchyma is evaluated systematically: Portal tracts with duct , artery and vein, portal-lobular interface , hepatocytes , and…
