Renal Lymphangiectasis
Renal Lymphangiectasis Aleksandr Vasilyev, MD, PhD Key Facts Terminology Hamartomatous or acquired obstructive lesion resulting in cystic dilatation of kidney lymphatics Clinical Issues No age or gender predilection; may be…
PATHOLOGY & LABORATORY MEDICINE
Uric Acid Nephropathy/Gout
Uric Acid Nephropathy/Gout Shane M. Meehan, MBBCh Key Facts Terminology Intrarenal precipitation of uric acid associated with hyperuricemia Etiology/Pathogenesis Decreased uric acid excretion (75-90%) Overproduction of uric acid (10-25%) Clinical…
Ureter: Margins
Ureter: Margins A small length of ureter received for frozen section should be oriented and embedded in such a way that a complete cross section of the lumen is obtained….
Ethylene Glycol
Ethylene Glycol Shane M. Meehan, MBBCh Key Facts Terminology Oxalosis due to ethylene glycol ingestion Etiology/Pathogenesis Renal injury due to calcium oxalate deposition and other toxins like glycolic acid Clinical…
Glomerulocystic Disease
Glomerulocystic Disease Aleksandr Vasilyev, MD, PhD Anthony Chang, MD Key Facts Terminology 2-3x dilatation of Bowman space, > 5% of glomeruli in absence of other kidney diseases GCKD reserved for…
Dense Deposit Disease
Dense Deposit Disease A. Brad Farris, III, MD Key Facts Terminology C3 nephropathy with very electron-dense deposits within GBM and mesangium Clinical Issues Rare (1-3 cases/million) Primarily children 5-15 years…
Bartter Syndrome
Bartter Syndrome Shane M. Meehan, MBBCh Key Facts Terminology Normotensive hyper-reninemic hyperaldosteronism with hypokalemic alkalosis and hyperplasia of juxtaglomerular apparatus Etiology/Pathogenesis 5 types of loss-of-function mutations of genes affecting ion…
Endocarditis
Endocarditis A. Brad Farris, III, MD Key Facts Terminology GN following infection of heart valves Etiology/Pathogenesis Subacute bacterial endocarditis (SBE) e.g., Streptococcus viridans infecting a rheumatic heart Acute bacterial endocarditis…
Karyomegalic Interstitial Nephritis
Karyomegalic Interstitial Nephritis Robert B. Colvin, MD Key Facts Etiology/Pathogenesis Idiopathic Genetic risk factor suspected, but unproved DNA toxins suspected in some cases (ochratoxin) Clinical Issues Rare; < 30 cases…
Type III Collagen Glomerulopathy
Type III Collagen Glomerulopathy Helen Liapis, MD Joseph Gaut, MD, PhD Key Facts Terminology Idiopathic glomerular disease defined by accumulation of mesangial and subendothelial type III collagen Clinical Issues Rare…
