Post-transplant Lymphoproliferative Disorder, Early Lesions and Polymorphic C. Cameron Yin, MD, PhD Pei Lin, MD Key Facts Etiology/Pathogenesis Epstein-Barr virus infection and impaired host immunosurveillance important 80% of all PTLDs…

Nodal Marginal Zone B-cell Lymphoma Pei Lin, MD Key Facts Clinical Issues Age: 5th-6th decades No evidence of extranodal or splenic lymphoma Can transform to diffuse large B-cell lymphoma Microscopic…

Subcutaneous Panniculitis-like T-cell Lymphoma Tariq Muzzafar, MBBS Key Facts Terminology Cytotoxic T-cell lymphoma that preferentially involves subcutaneous tissue and expresses TCR-αβ Definition of SPTCL substantially revised in WHO 2008 classification…

Enteropathy-associated T-cell Lymphoma Sa A. Wang, MD Key Facts Terminology T-cell lymphoma of intestine Arises from intraepithelial T cells Etiology/Pathogenesis Classical cases of EATL arise in patients with evidence of…

Palisaded Myofibroblastoma L. Jeffrey Medeiros, MD Key Facts Terminology Intranodal palisaded myofibroblastoma Synonyms Intranodal hemorrhagic spindle-cell tumor with amianthoid fibers Myofibroblastoma Clinical Issues Rare benign tumor of probable myofibroblastic origin…

Peripheral T-cell Lymphoma, Not Otherwise Specified James M. You, MD, PhD Key Facts Clinical Issues PTCL represents approximately 6.0% of all non-Hodgkin lymphomas Mainly arises in middle-aged adults; rare in…

Primary Effusion Lymphoma (PEL) and Solid Variant of PEL Francisco Vega, MD, PhD Key Facts Etiology/Pathogenesis PEL arises from HHV8-infected B cells frequently coinfected by EBV Associated with HIV infection…

ALK+ Anaplastic Large Cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology CD30(+) lymphoma of T- or null cell lineage having chromosomal abnormalities involving 2p23 (ALK locus) Clinical Issues Children…

Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type Sa A. Wang, MD Key Facts Terminology Primary cutaneous DLBCL composed exclusively of large transformed cells Clinical Issues 20% of primary cutaneous…