Post-transplant Lymphoproliferative Disorder, Monomorphic Pei Lin, MD L. Jeffrey Medeiros, MD Key Facts Terminology Monomorphic PTLDs fulfill criteria for lymphomas as observed in immunocompetent patients Etiology/Pathogenesis Epstein-Barr virus (EBV) infection…
Plasmablastic Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Diffuse neoplasm with immunoblastic or plasmablastic features and plasma cell immunophenotype Aggressive clinical course Poor prognosis Etiology/Pathogenesis Associated with immunodeficiency HIV…
Follicular Dendritic Cell Sarcoma Sa A. Wang, MD Key Facts Terminology Neoplastic proliferation of follicular dendritic cells Clinical Issues Presents as slow-growing, painless mass Lymph nodes Extranodal sites; Waldeyer ring…
Lymphomas Associated with FGFR1 Abnormalities Roberto N. Miranda, MD Key Facts Terminology Lymphoblastic lymphoma occurring in patients with 8p11 myeloproliferative syndrome EMS is aggressive disease associated with FGFR1 gene abnormalities;…
B-cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-cell Lymphoma and Classical Hodgkin Lymphoma Francisco Vega, MD, PhD Key Facts Terminology B-cell lymphoma, unclassifiable, with features intermediate between DLBCL…
Langerhans Cell Sarcoma Sa A. Wang, MD Key Facts Terminology Neoplastic proliferation of Langerhans cells with overtly malignant cytologic features Clinical Issues LCS most often presents as de novo mass…
Primary Mediastinal (Thymic) Large B-cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Diffuse large B-cell lymphoma (DLBCL) arising in mediastinum of putative thymic B-cell origin Clinical Issues Most frequent…
Angioimmunoblastic T-cell Lymphoma Sa A. Wang, MD Key Facts Terminology Peripheral T-cell lymphoma derived from CD4(+) follicular helper T cells characterized by Lymphadenopathy, systemic disease, and, usually, immunodysregulation and immunodeficiency…
Lymphoplasmacytic Lymphoma and Waldenstrom Macroglobulinemia Pei Lin, MD Key Facts Terminology LPL is a neoplasm of small B lymphocytes ± plasmacytoid features and plasma cells that does not meet criteria…
Interdigitating Dendritic Cell Sarcoma Wesley O. Greaves, MD L. Jeffrey Medeiros, MD Key Facts Clinical Issues Wide age range Single lymph nodes most commonly involved Cervical, axillary, or inguinal groups…
