Microcystic Adnexal Carcinoma David Cassarino, MD, PhD Key Facts Terminology Microcystic adnexal carcinoma (MAC) Synonyms: Sclerosing sweat duct carcinoma, syringoid carcinoma Low-grade malignant adnexal tumor with follicular and ductal differentiation…
Squamoid “Eccrine” Ductal Carcinoma David Cassarino, MD, PhD Key Facts Terminology Squamoid “eccrine” ductal carcinoma (SEDC) Rare carcinoma with ductal and squamous features Clinical Issues Aggressive local recurrences, but no…
Eccrine Carcinoma Steven D. Billings, MD Key Facts Clinical Issues Typically present as plaque on scalp Locally aggressive Microscopic Pathology Infiltrative growth pattern, often with perineural invasion Tumor composed of…
Syringofibroadenoma Senait W. Dyson, MD Key Facts Clinical Issues Commonly on an extremity More common in women Usually solitary, hyperkeratotic plaque Multiple lesions might be associated with rare syndromes Microscopic…
Papillary Eccrine Adenoma Senait W. Dyson, MD Key Facts Terminology Rare benign adnexal tumor with eccrine differentiation Most authorities separate PEAs from tubular apocrine adenomas Clinical Issues Presentation: Firm or…
Primary Cutaneous Mucinous Carcinoma Senait W. Dyson, MD David Cassarino, MD, PhD Key Facts Terminology Malignant tumor with characteristic histology of epithelial islands “floating” in pools of mucin Clinical Issues…
Eccrine Hamartomas Christine J. Ko, MD Key Facts Microscopic Pathology Eccrine angiomatous hamartoma Eccrine glands normal (occasionally enlarged) or increased in number Endothelial cell-lined, thin-walled vascular spaces intimately admixed with…
Apocrine Carcinoma (Apocrine Adenocarcinoma) Christine J. Ko, MD David Cassarino, MD, PhD Key Facts Clinical Issues Axilla most common site, but other sites described No history of breast carcinoma Indolent…
Adenoid Cystic Carcinoma David Cassarino, MD, PhD Key Facts Terminology Adenoid cystic carcinoma (ACC) Rare adnexal tumor showing prominent cribriform pattern and perineural invasion Clinical Issues Up to 70% of…
