PATHOLOGY & LABORATORY MEDICINE

Molluscum Contagiosum

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Molluscum Contagiosum

Molluscum Contagiosum Talley Whang, MD Key Facts Etiology/Pathogenesis Caused by molluscum contagiosum viruses (poxvirus), transmitted by skin-to-skin contact Clinical Issues Primarily affects young children; also affects immunosuppressed individuals Dome-shaped papules…

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Impetigo

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Impetigo

Impetigo Irina Margaritescu, MD, DipRCPath Bruce R. Smoller, MD Key Facts Terminology Definition Acute, contagious superficial pyogenic infection of skin caused by staphylococci, streptococci, or both Clinical Issues Epidemiology Peak…

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Darier Disease

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Darier Disease

Darier Disease Irina Margaritescu, MD, DipRCPath Key Facts Etiology/Pathogenesis Autosomal dominant genodermatosis Mutations in gene ATP2A2 New mutations in ˜ 25% of cases Clinical Issues Age Typical onset in late…

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Chalazion

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Chalazion

Chalazion Larissa V. Furtado, MD Key Facts Etiology/Pathogenesis Chronic obstruction of meibomian or Zeis glands → retained meibomian secretions → chronic granulomatous inflammation Clinical Issues Occurs more frequently on the…

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Epidermolysis Bullosa, Inherited

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Epidermolysis Bullosa, Inherited

Epidermolysis Bullosa, Inherited Jessica M. Comstock, MD Key Facts Terminology Heterogeneous group of noninflammatory inherited disorders characterized by development of blisters or erosions after minor trauma Etiology/Pathogenesis Autosomal dominant or…

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Acropustulosis of Infancy

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Acropustulosis of Infancy

Acropustulosis of Infancy Larissa V. Furtado, MD Key Facts Terminology Infantile acropustulosis Clinical Issues Predominantly occurs during first 3 years of life Not limited to young children Involves primarily acral…

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Protothecosis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Protothecosis

Protothecosis Gretchen Frieling, MD Chad Jessup, MD, MS Martin Mihm, MD Key Facts Terminology Rare algal infection caused by organisms of genus Prototheca Etiology/Pathogenesis Principle defense thought to be neutrophilic…

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Onchocerciasis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Onchocerciasis

Onchocerciasis George R. Collins, DO Joseph Susa, DO Clay J. Cockerell, MD Key Facts Etiology/Pathogenesis Caused by filarial nematode Onchocerca volvulus Transmitted to humans via bite of black fly of…

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Leishmaniasis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Leishmaniasis

Leishmaniasis Brian J. Hall, MD Francisco G. Bravo, MD Key Facts Etiology/Pathogenesis Identification of kinetoplast allows for distinction from other commonly confused microorganisms Clinical Issues 4 main types of clinical…

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Tuberculosis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Tuberculosis

Tuberculosis Francisco G. Bravo, MD Patricia J. Alvarez, MD Key Facts Etiology/Pathogenesis Mycobacterium tuberculosus is etiologic agent Mechanism of propagation is by direct inoculation, contiguous infection, and hematogenous spread Clinical…

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