Acropustulosis of Infancy



Acropustulosis of Infancy


Larissa V. Furtado, MD









Small vesicles and erythematous papules involve the acral skin of this infant with acropustulosis of infancy (AI). (Courtesy S. Vanderhooft, MD.)






Biopsy specimen of AI shows a subcorneal, intraepidermal pustule with a predominance of eosinophils image. (Courtesy M. Chaffins, MD.)


TERMINOLOGY



Synonyms



  • Infantile acropustulosis


ETIOLOGY/PATHOGENESIS


Etiology



  • Unknown


  • Scabies infestations may precede or be associated with AI


CLINICAL ISSUES


Epidemiology



  • Age



    • Predominantly occurs during first 3 years of life


    • Not limited to young children


    • Rare congenital cases have been reported


  • Gender



    • Although initial reports described male predominance, larger series have shown no gender predilection


  • Ethnicity



    • Larger series have shown no ethnic predilection

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Acropustulosis of Infancy
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