Onchocerciasis



Onchocerciasis


George R. Collins, DO

Joseph Susa, DO

Clay J. Cockerell, MD










Numerous hyperpigmented papules image, lichenified plaques image, and nodules image are seen here diffusely involving the lower leg of a patient who recently returned from Africa.






A large unilateral right inguinal mass, composed of enlarged lymph nodes, hernia, and worm(s), involves folds of inelastic, atrophic skin in the area and results in the “hanging groin” sign.


TERMINOLOGY


Synonyms



  • “River blindness”


Definitions



  • Chronic systemic filarial infection most commonly involving skin and eyes


ETIOLOGY/PATHOGENESIS


Infectious Agents



  • Caused by filarial nematode Onchocerca volvulus


  • Lifecycle



    • Transmitted to humans via bite of Simulium black fly, found near free-flowing waterways


    • Bite results in microfilariae entering skin and developing into adult worms in subdermal connective tissues

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Onchocerciasis
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