Protocol for the Examination of Rhabdomyosarcoma Specimens Rhabdomyosarcoma and Related Neoplasms: Resection or Biopsy Surgical Pathology Cancer Case Summary (Checklist) Procedure ____Biopsy ____Excision, local ____Excision, radical ____Excision, compartmentectomy Amputation (specify…
Myopericytoma Thomas Mentzel, MD Key Facts Terminology Benign perivascular neoplasm composed of perivascular myoid tumor cells (myopericytes) Myopericytoma forms morphologic spectrum with angioleiomyoma, myofibroma, glomus tumor, and so-called hemangiopericytoma Clinical…
Rhabdomyoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign tumor with skeletal muscle differentiation Extracardiac tumors can be of adult or fetal histologic type Etiology/Pathogenesis Some fetal rhabdomyomas associated…
Glomus Tumors Thomas Mentzel, MD Key Facts Terminology Perivascular myogenic mesenchymal neoplasm composed of cells closely resembling smooth muscle cells of normal glomus body Clinical Issues Distal extremities, especially in…
Neuroblastoma and Ganglioneuroblastoma Jessica Comstock, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant tumor derived from primordial neural crest cells Clinical Issues 3rd most common malignant tumor in…
Hemangiopericytoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Tumor with diffuse pattern of branching, dilated, thin-walled blood vessels composed of short spindle cells Many tumor types have pericytomatous pattern,…
Fibroosseous Pseudotumor David R. Lucas, MD Key Facts Terminology Benign reactive ossifying fibroblastic proliferation most often affecting skin and soft tissue in digits of hands and feet Clinical Issues Proximal…
Osteoma Cutis David S. Cassarino, MD, PhD Key Facts Etiology/Pathogenesis Primary: May be part of Albright hereditary osteodystrophy or other genetic syndromes Secondary: Associated with preexisting lesions, such as nevi,…
Heterotopic Mesenteric Ossification Elizabeth A. Montgomery, MD Key Facts Terminology Intraabdominal myositis ossificans Metaplastic, probably reactive process variably associated with trauma Clinical Issues Adults; mean age: 50-60 years Small bowel…
Myositis Ossificans Elizabeth A. Montgomery, MD Key Facts Clinical Issues Mean age: ˜ 30 years (range: 1-95 years) M > F (˜ 3:2) for classic lesions F > M for…
