Bronchial Malignant Melanoma
Bronchial Malignant Melanoma Key Facts Clinical Issues Incidence Approximately 0.01% of all lung neoplasms More common in adults in 6th decade of life Symptoms Cough Dyspnea Chest pain hemoptysis Fever…
PATHOLOGY & LABORATORY MEDICINE
IgG4 Sclerosing Lung Disease
IgG4 Sclerosing Lung Disease Key Facts Terminology Systemic disease of unknown etiology characterized by elevated production of IgG4(+) plasma cells and tissue stromal sclerosis Clinical Issues Slowly progressive disease with…
Neuroendocrine Carcinoma (Including Small Cell Carcinoma)
Neuroendocrine Carcinoma (Including Small Cell Carcinoma) Key Facts Terminology Spectrum of neoplasms ranging from low- to high-grade malignancy Clinical Issues Paraneoplastic syndromes Macroscopic Features Endobronchial or intraparenchymal tumor 0.5 to…
Pulmonary BALT Hyperplasia
Pulmonary BALT Hyperplasia Key Facts Terminology Polyclonal proliferation of small lymphocytes arising within lung parenchyma Etiology/Pathogenesis Commonly associated with underlying autoimmune disorders such as Sjögren syndrome, rheumatoid arthritis, and collagen…
Mixed Tumor
Mixed Tumor Key Facts Terminology Synonym: Pleomorphic adenoma (PA) Biphasic neoplasm with epithelial/myoepithelial and mesenchymal differentiation Clinical Issues Symptoms Cough Dyspnea Chest pain Hemoptysis Prognosis Excellent for benign tumors Malignant…
Hodgkin Lymphoma
Hodgkin Lymphoma Key Facts Clinical Issues HL arising primarily in lungs is extremely rare Pulmonary involvement is most often seen in course of regional or systemic dissemination Night sweats Mediastinal,…
Pulmonary Artery Sarcoma
Pulmonary Artery Sarcoma Key Facts Terminology Synonym: Intimal sarcoma Malignant mesenchymal tumor originating from wall of pulmonary trunk Clinical Issues Cough Chest pain Shortness of breath Fatigue Syncope Macroscopic Features…
Mucoepidermoid Carcinoma
Mucoepidermoid Carcinoma Key Facts Terminology Epithelial neoplasm composed of epidermoid and clear cells admixed with mucus-secreting cells (mucocytes) Clinical Issues Prognosis Depends on grading of tumor For low-grade tumors, prognosis…
Osteosarcoma
Osteosarcoma Key Facts Terminology Malignant mesenchymal neoplasm with osseous differentiation Clinical Issues Incidence Osteosarcomas of lung are exceedingly rare with > 30 cases reported Pulmonary osteosarcomas appear to be more…
Angiosarcoma
Angiosarcoma Key Facts Terminology Hemangiosarcoma Clinical Issues Symptomatology Shortness of breath Hemoptysis Frank pulmonary hemorrhage Macroscopic Features Single or multiple pulmonary nodules Microscopic Pathology Epithelioid malignant cells forming vascular channels…
