Diffuse Large Cell Lymphoma Key Facts Etiology/Pathogenesis May arise from progressive transformation of preexisting low-grade MALT lymphoma Clinical Issues Adults from 50-70 years of age Usually peripheral in location Microscopic…
Benign Metastasizing Leiomyoma Key Facts Clinical Issues 30-50 years of age Exclusively observed in women Lesions are usually multiple and may be bilateral, suggesting metastatic disease Macroscopic Features Well-circumscribed, tan-white…
Ganglioneuroblastoma Key Facts Terminology P-GNB Clinical Issues Incidence GNBs are exceedingly rare tumors in the lung Cases described have been in adult patients There is no gender predilection Symptoms Cough…
Juvenile Xanthogranuloma Key Facts Terminology Abbreviation: Pulmonary juvenile xanthogranuloma (JXG) Definition Non-Langerhans histiocytic lesion Etiology/Pathogenesis Contrary to other histiocytic lesions, cell of origin for JXG is unknown Plasmacytoid monocyte has…
Angiolymphoid Hyperplasia with Eosinophilia Key Facts Terminology Angiolymphoid hyperplasia with eosinophilia (ALHE) Epithelioid hemangioma Clinical Issues Presentation Cough Dyspnea Asthma Treatment of choice: Complete surgical resection Lobectomy Wedge resection Prognosis:…
Inflammatory Pseudotumor Key Facts Terminology Myofibroblastic tumor Etiology/Pathogenesis Some cases linked to HHV-8 Clonality demonstrated in some cases Clinical Issues Tumor more common in young individuals < 40 years old…
Lymphomatoid Granulomatosis Key Facts Terminology Angiocentric lymphoproliferative disorder composed of Epstein-Barr-infected B cells admixed with reactive T cells Clinical Issues Cough Dyspnea Microscopic Pathology Sheets of mixed, polymorphous atypical lymphoreticular…
Plasmacytoma Key Facts Clinical Issues Incidence Primary plasmacytomas of lung are rare May represent approximately 5% of all extramedullary plasmacytomas Tumor has been described essentially in adults Symptoms Cough Hemoptysis…
Atypical Adenomatous Hyperplasia Key Facts Terminology Microscopic proliferation of atypical alveolar lining cells measuring < 5 mm in greatest diameter Clinical Issues Incidental microscopic finding in lung tissues removed for…
Pulmonary BALT Lymphoma Key Facts Clinical Issues Most common presentation is solitary mass on routine imaging studies Most patients are asymptomatic Favorable prognosis; 5-year survival in approximately 85-95% Image Findings…
