Asbestos-related Interstitial Fibrosis Key Facts Terminology Asbestosis Interstitial pulmonary fibrosis secondary to inhalation of asbestos dust Etiology/Pathogenesis 2 types of asbestos fibers have been identified Serpentine Chrysotile (more common in…
Metastatic Carcinoma Key Facts Clinical Issues Cough, chest pain, dyspnea, hemoptysis, and pleural effusion are most common presenting symptoms Most common primary sites: Genital, gastrointestinal and genitourinary tracts, pancreatohepatobiliary tract,…
Coccidioidomycosis Key Facts Terminology Pulmonary infection caused by inhalation of fungal spores of Coccidioides immitis Clinical Issues Organism is endemic in Southwestern United States, Mexico, and Central and South America…
Overview of Malignant Pleural Neoplasms Cut section of the lung in a patient with malignant pleural mesothelioma shows a thick rind of whitish tumor tissue surrounding the outer surface of…
Wegener Granulomatosis Key Facts Etiology/Pathogenesis No definitive etiology is known for WG Clinical Issues Incidence More common in adults, usually in 5th decade of life Since WG is systemic and…
Extrinsic Allergic Alveolitis Key Facts Terminology Hypersensitivity pneumonitis (HP) Granulomatous lung disease secondary to inhalation of organic antigens or chemicals Etiology/Pathogenesis History of exposure to organic antigens Saccharopolyspora tectivirgula in…
Hard Metal Pneumoconiosis Pneumonitis Key Facts Terminology Type of pneumonitis caused by exposure to hard metal (cobalt) Etiology/Pathogenesis Exposure to hard metal Hard metal is combination of tungsten with cobalt…
Adenovirus Key Facts Clinical Issues Accounts for about 10% of all pneumonias in children and infants Epidemics have been reported in military personnel Microscopic Pathology 2 major patterns of lung…
Metastatic Malignant Melanoma Key Facts Clinical Issues Lung is frequent site of metastasis for malignant melanoma Middle-aged to elderly patients Image Findings Multiple, well-defined nodules in periphery of lungs Endobronchial…
Allergic Angiitis and Granulomatosis (Churg-Strauss) Key Facts Terminology Systemic process characterized by presence of vasculitis, blood eosinophilia, and asthma Etiology/Pathogenesis No definitive etiology has been defined for Churg-Strauss syndrome Probably…
