Hematologic Malignancies Primary non-Hodgkin lymphomas (NHLs) of the lung are relatively rare, comprising fewer than 1% of primary pulmonary neoplasms and fewer than 10% of extranodal lymphomas. The most common…

Nodular Amyloidosis Timothy C. Allen Mary L. Ostrowski Nodular amyloidosis is a rare lesion that generally presents incidentally in adults as a 1- to 4-cm slow-growing nodule. The nodules are…

Sarcoidosis Abida K. Haque Sarcoidosis is a systemic disease of unknown etiology, characterized by formation of noncaseating granulomas in the lung, lymph nodes, and multiple other organs. Patients are often…

Berylliosis Abida K. Haque Beryllium is a lightweight metal used in the aerospace and electronic industries and in the manufacture of thermal couplings, atomic reactors, and fluorescent lights. Exposure to…

Necrotizing Sarcoid Granulomatosis Alvaro C. Laga Timothy C. Allen Abida K. Haque Necrotizing sarcoid granulomatosis (NSG) is an unusual pulmonary lesion first described by Liebow and thought to represent a…

Inflammatory Pseudotumor/Inflammatory Myofibroblastic Tumor Handan E. Zeren Angela Shen Alvaro C. Laga Timothy C. Allen Philip T. Cagle Many issues regarding inflammatory pseudotumor and inflammatory myofibroblastic tumor (IMT) are unresolved,…

Pulmonary Hyalinizing Granuloma Alvaro C. Laga Timothy C. Allen Keith M. Kerr Philip T. Cagle Pulmonary hyalinizing granuloma is a rare non-neoplastic fibrosclerosing inflammatory lung condition. Lesions are often identified…

Sarcoid-Like Reaction Abida K. Haque Sarcoid-like epithelioid granulomas may be seen in lung parenchyma, and in thoracic lymph nodes draining areas of a lung with carcinoma.

Metaplastic, Dysplastic, and Premalignant Lesions Metaplastic, dysplastic, and other premalignant proliferations are often precursors to lung cancers. These lesions are important to recognize for diagnostic purposes, for their importance in…