Systemic Lupus Lymphadenopathy Definition Lymphadenopathy associated with systemic lupus erythematosus (SLE). Synonym Lupus lymphadenopathy; lupus lymphadenitis. Epidemiology Systemic lupus erythematosus has a worldwide distribution, with differences in prevalence related to…
Kikuchi Lymphadenopathy Synonyms Kikuchi disease; Kikuchi Fujimoto lymphadenopathy; Histiocytic necrotizing lymphadenitis. Definition Subacute necrotizing regional lymphadenopathy associated with mild fever, more common in young Asian people. Epidemiology Described independently in…
Sinus Histiocytosis with Massive Lymphadenopathy Definition A rare benign disorder of histiocytes characterized histologically by intracellular engulfment of lymphocytes. Synonyms Rosai-Dorfman disease; Histiocytose lipidique ganglionnaire pseudotumorale de Destombes; lymphadenitis with…
Kimura Lymphadenopathy Definition Kimura disease is a chronic inflammatory disorder prevalent in Asians. It involves subcutaneous tissues and lymph nodes predominantly in the head and neck region and is characterized…
Progressive Transformation of Germinal Centers Definition Progressive transformation of germinal centers (PTGC) is a benign reaction pattern in lymph nodes. The lesion of PTGC is composed of large nodules in…
Atypical Lymphoid Hyperplasia Definition Hyperplasia with atypical histologic or cytologic features of lymph nodes (or of other lymphoid organs), suggestive but not diagnostic of lymphoma. Pathogenesis Atypical lymphoid hyperplasia (ALH)…
Reactive Lymphoid Hyperplasia Definition Enlargement of lymph nodes or other lymphoid organs as a consequence of hyperplasia of some or all of the cellular components, reflecting stimulation of the lymphoid…
Introduction Lymphadenopathies are reactive processes of lymph nodes in response to a variety of exogenous and endogenous stimulants. The etiology and pathogenesis of many lymphadenopathies are still unknown; thus, the…
Filaria Lymphadenitis Definition Lymphadenitis caused by infection with filarial parasites. Epidemiology Filaria organisms are nematode worms of various species with a distinct geographic distribution. Wuchereria bancrofti is prevalent in Africa…
Leishmania Lymphadenitis Definition Lymphadenitis caused by infection with protozoa of the genus Leishmania. Epidemiology Leishmaniasis is endemic in Asia, South America, Africa, where it is caused by L. donovani, and…
