Fig. 4.1. Lymphoma with convoluted nuclei. Nuclear inclusions exist in various forms Viruses may be visualized by negative staining of whole particles or in thin sections. See section on nonneoplastic…

Fig. 21.1. Myositis ossificans (gross) forming a circumscribed mass with a bony shell and a hemorrhagic fibrous center (A). Myositis ossificans (micro) at frozen section a well developed “zonation” is…

Fig. 26.1. (A) Mediastinal granuloma . Enlarged, matted lymph nodes replaced by fibrocaseous granulomas (scale = 1 cm). (B) Fibrocaseous granuloma with central cavitation within lymph node. (C) Budding yeast-like organisms consistent…

Fig. 37.1. Fibroepithelial polyp of the ureter.   ♦ Chronic inflammatory cell infiltrate and xanthoma cells may be present   Ureteral Endometriosis Clinical ♦ Mean age at diagnosis is 51…

Fig. 11.1. Detection of the translocation t(14;18) by FISH. Fluorescent probes specific for BCL2 (red), IGH (green), and the chromosome 18 centromere (aqua = control) were hybridized to tumor cell spreads. Panel…

Fig. 13.1. Down syndrome – brushfield spots on irides (A). Single transverse palmar creases and fifth finger clinodactyly (B). Gap between first and second toe (C).   ♦ Developmental delay,…

Tumor Cytogenetic alteration Fusion genes [significance] Alveolar rhabdomyosarcoma t(2;13)(q35;q14) PAX3–FOXO1(FKHR) Alveolar rhabdomyosarcoma t(1;13)(p36;q14) PAX7–FOXO1(FKHR) – [favorable prognosis] Alveolar soft part sarcoma t(X;17)(p11;q25) TFE3–ASPSCR1(ASPL) – [sensitive to MET inhibitors] Clear cell…

Fig. 9.1. Barcode scanning at gross station equipped with barcoding scanners for material tracking.   Historical Perspective 1960–2000 ♦ Interdisciplinary field at the cross section of biology, medicine, computer science,…

Fig. 8.1. Logical diagram for the sequence of procedures involved for ascertaining medicolegal jurisdiction, validating a consent, identifying the body, and examining the body at autopsy.   Trauma ♦ Review…