Fig. 36.1 A large necrotic metastasis which has necessitated a nephrectomy after chemotherapy. The testis is also seen below with a much smaller mass showing teratoma The techniques used therefore…
Fig. 29.1 Clear cell RCC, ISUP grade 2. H & E × 100 Cysts are a common element of VHL. They vary in size, and may be lined by rows…
Fig. 37.1 Seminoma with marked lymphoplasmacytic infiltrate overwhelming the tumor cells 2. Intertubular seminoma: Seminoma cells usually form a solid sheet and displace the seminiferous tubules. However, the cells…
Fig. 34.1 Descent of the testis. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography © 2014. All Rights Reserved.) Embryology also explains the metastatic patterns of spread…
Fig. 5.1 a Radical prostatectomy, mucinous adenocarcinoma (low magnification). b Radical prostatectomy, mucinous adenocarcinoma (high magnification) Prostatic Ductal Adenocarcinoma Prostatic ductal adenocarcinoma is a rare variant of prostate cancer that…
Fig. 40.1 Seminoma in a needle biopsy of the retroperitoneum. a H&E stain. b OCT3/4 showing nuclear immunoreactivity. c CD117 showing cytoplasmic/membranous staining. d CD20 staining surrounding lymphocytes Molecular Markers…
Fig. 30.1 Expression of PAX8 in normal and neoplastic renal tissues. PAX8 is expressed throughout renal tubules, but more intensely in distal tubules and collecting ducts (a, b), and urothelium…
Fig. 13.1 Reactive urothelial atypia (H&E). a and b Reactive urothelial atypia is characterized by mild nuclear enlargement with fine, evenly distributed nuclear chromatin and small pinpoint nucleoli. Intraurothelial inflammatory…
Established indications Rule out metastasis of extrarenal primary involving kidney Rule out lymphoma involving kidney Rule out renal mass caused by a benign condition such as infection Patients with unresectable…
Renal cell carcinoma (RCC) Benign Clear cell RCC Oncocytoma Multilocular cystic RCC Papillary adenoma Papillary RCC Metanephric adenoma Chromophobe RCC Angiomyolipoma Collecting duct RCC Epithelioid AML Medullary carcinoma Cystic nephroma…
