Rare Secondary Tumors of the Pancreas
Fig. 15.1 Metastatic breast cancer. Histologically, the neoplastic cells involve the duodenal wall (a) and pancreatic lobules, replacing normal acinar tissue (b) With regard to the location, 25% of the…
GENERAL SURGERY
Rare Variants of Ductal Adenocarcinoma of the Pancreas
, Marco Dal Molin, Federica Pedica, Paola Capelli, Mirko D’Onofrio and Giovanni Butturini (1) Surgery Unit, Casa di cura, “Dr. P. Pederzoli”, Peschiera del Garda, (VR), Italy Abstract Histologic variants of ductal adenocarcinoma are neoplasms…
Solid-pseudopapillary, Acinar, and Other Cystic Neoplasms
Fig. 4.1 Solid-pseudopapillary neoplasm. Pseudopapillary structures with fibrovascular cores (left) and a solid area showing small monomorphic cells (right) Fig. 4.2 Solid-pseudopapillary neoplasm. Cytoplasmic and nuclear β-catenin immunostaining in neoplastic…
Pathology and Genetics
Well-differentiated neuroendocrine neoplasm (NEN) NEN G1 NEN G2 Poorly differentiated neuroendocrine carcinoma (NEC) Large-cell NEC Small-cell NEC 8.3 Pathology Macroscopically, PanNENs are usually solitary, solid masses, from 1 to 5…
Mucinous Cystic Neoplasms
Fig. 3.1 Mucinous cystedenoma ultrasound. The sonographic scan shows a hypoechoic lesion in the head of the pancreas. The lesions has a macrocystic pattern, as indicated by the large anechoic…
Functional Imaging and Peptide Receptor Radionuclide Therapy
Fig. 11.1 Octreotide amino acid structure. (Reproduced from [2], with permission) The presence of octreotide-binding SSTRs on NENs allows the in vivo functional visualization of these tumors with the use…
Serous Cystic Neoplasms
Fig. 2.1 Serous cystadenoma: ultrasound (US). Sonographic scans show a hypoechoic lesion with sharp margins in the head of the pancreas (black arrow). Within the lesion, anechoic areas can be…
Primary Non-epithelial Tumors of the Pancreas
Fig. 16.1 Metastatic leioomyosarcoma. a Gross appearance of a mesenchymal tumor: the tumor is well circumscribed and composed of soft tissue. b Histologically, the tumor exhibits high cellularity and is…
Targeted and Other Non-receptor-mediated Therapies
Author (year) CT (mono-CT) Type Total pts n° n° PanNETs PFS (months) OS (months) RR (%) Brizzi et al. (2009) [42] 5FU (+Octreotide LAR) NEN 29 13 22.6 NR 24.1 …
Surgical Therapy
2. Kulke MH, Anthony LB, Bushnell DL et al (2010) NANETS treatment guidelines: well-differentiated neuroendocrine tumors of the stomach and pancreas. Pancreas 39:735–752PubMedCrossRef 3. Falconi M, Bartsch DK, Eriksson B…
