Fig. 1 Receptor desensitization mechanism of vascular hyporesponsiveness. The signal transductions for receptor desensitization include three pathways. One is the internalization of surface receptors, the second pathway is receptor transcription regulation…
Genomics Biomarkers (reference) Patients/animals (reference) Changes Clinical relevance (reference) SNP TLR1 [28] 1961 trauma patients −7202G +742A/G (Asn248Ser) Association with increased mortality after traumatic injury and sepsis CD14 [30–33] 14…
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_14 Novel Inflammatory and Immunomodulatory Mediators in Sepsis Cindy Cen1, Monowar Aziz2 and Ping Wang1, 2 (1) Department of Surgery, Hofstra Northwell School…
Gene Chrome location Variation Population Study size Fuctional effects Associated clinical phenotype References TLR1 4p14 −7202A/G(rs5743551) Whites 1498 Higher mortality with sepsis after traumatic injury [11] 742A/G(Asn248Ser) (rs4833095), Whites 1498 …
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_12 Early Prediction and Prevention of Trauma-Related Infection/Sepsis Xiaoyuan Ma1, Lixing Tian1 and Huaping Liang1 (1) State Key Laboratory of Trauma, Burns and…
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_11 Metabolic Changes and Nutrition Therapy in Burn Patients Xi Peng1 (1) State Key Laboratory of Trauma, Burns and Combined Injury,…
Fig. 1 Phases of the response to injury The ebb phase, also named acute phase, usually lasts 1–3 days. The clinical presentation of ebb phase is hypometabolism, decreased temperature, decreased energy expenditure…
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_9 Acute Coagulopathy of Trauma-Shock Baiqiang Li1 and Haichen Sun2 (1) Jinling Hospital, Research Institute of General Surgery, Nanjing University Medical School,…
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_1 Damage Control Theory in Treatment of Multiple Injuries Xiangjun Bai1 (1) Department of Trauma Surgery, Tongji Hospital, Hua Zhong University…
© Springer Nature Singapore Pte Ltd. 2017Xiaobing Fu and Liangming Liu (eds.)Advanced Trauma and Surgery10.1007/978-981-10-2425-2_5 Current Developments on Traffic Medicine Jihong Zhou1 and Jun Qiu1 (1) State Key Laboratory of Trauma, Burns and Combined Injury, Institute…
