Scaffold Manufacturer Polymer Coating Drug Resorption time (months) Igaki-Tamai Kyoto Medical PLLA None None 24 BVS 1.0 Abbott Vascular PLLA PDLLA Everolimus 24 BVS 1.1 Abbott Vascular PLLA PDLLA Everolimus…

Fig. 17.1 Working principle of a biosensor. The analyte is specifically recognized by the bioelement. A biochemical reaction occurs upon the event of recognition leading to the generation of a signal,…

Fig. 16.1 Sequence of events leading to thrombus formation on blood-contacting surfaces (e.g., implanted medical devices) Fig. 16.2 Simplified schematic of the coagulation cascade, where clotting is initiated by either surface contact…

Fig. 6.1 Eyeball anatomy The fibrous layer is composed of a rear opaque part, the sclera, and anterior and transparent, the cornea. The cornea is the transparent frontal window of the…

Clinical steps Etching Primer Resin Etch-and-rinse (3-steps) Phosphoric acid (30–35 %) HEMA, organic solvent (ethanol/acetone/water), proprietary monomers Hydrophilic and hydrophobic monomers (HEMA, TEGDMA, Bis-GMA, UDMA), initiators Etch and rinse (2-step) Phosphoric…

Fig. 10.1 Representation of EPR effect This occurs because of the abnormalities of tumor vasculature, namely hypervascularization, aberrant vascular architecture, extensive production of vascular permeability factors and lack of lymphatic drainage…

Fig. 11.1 Medicines can be designed: (i) to exert a local effect on the application site by means of drug release and penetration in surrounding cells (a), (ii) to exert a…

Designation Title F451-08 Standard specification for Acrylic Bone Cement F639-09 Standard specification for Polyethylene Plastics for medical applications F648-14 Standard specification for Ultra-High-Molecular-Weight Polyethylene Powder and Fabricated Form for surgical…

Fig. 4.1 Mammalian cell adhesion onto a biomaterial. a Initial contact between the cell and the biomaterial conditioned with serum proteins. b Bonding between cell surface receptors and protein adhesion ligands….

(7.1) where p is the differential pressure across the length of the pore, D is the pore diameter, γ is the surface tension of the wetting liquid; and θ is…