Whilst the practice of pharmacology is to ultimately reach an end goal of understanding pharmacodynamics (what the drug does to the body), scientists and clinicians also need to understand what…
Pharmacology concerns the study of how drugs affect the function of host tissues or combat infectious organisms. In most cases, drugs bind selectively to target molecules within the body, usually…
A drug has to be demonstrated to be reasonably safe and effective before it can enter the clinic (see Chapter 10 ). An integrated risk assessment will be made on…
Drug regulation seeks to ensure the quality of the whole process of making and using a new medicine. Thus there are strict regulatory requirements to adhere to on the synthesis,…
The action of drugs is usually measured by bioassay, which is the measurement of potency or activity of a drug using a biological response, using the principles of drug action…
Drug discovery has evolved in the last 50–60 years from a purely phenotypic screening approach (compound libraries subjected to systems-based assays to identify compounds with biological effects) towards a target-based…
Pharmacology is derived from the ancient Greek word for a drug, pharmakon, and is the study of how drugs and xenobiotics affect body function and also how the body will…
A Call to Action There are risks and costs to a program of action. But they are far less than the long-range risks and costs of comfortable inaction. —John F….
Making Your Clinic a Lean, Mean, Vaccinating Machine Alone we can do so little; together we can do so much. —Helen Keller We, as clinicians, can do everything right. We…
It’s a Jungle Out There: Navigating Vaccine Advice in the News and on the World Wide Web The greatest enemy of knowledge is not ignorance, it is the illusion of…
