Low-Grade Myofibroblastic Sarcoma Thomas Mentzel, MD Key Facts Terminology Low-grade myofibroblastic sarcoma represents distinct atypical myofibroblastic neoplasm with fibromatosis-like morphologic features Clinical Issues Occurs frequently in head and neck region…
Infantile Fibrosarcoma Thomas Mentzel, MD Key Facts Terminology Occurs in infants and young children; represents low-grade fibrosarcoma that carries favorable prognosis Clinical Issues Congenital or arises in 1st two years…
Solitary Fibrous Tumor Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Fibroblastic mesenchymal tumor with prominent hemangiopericytic branching vascular pattern Initially described in pleura Occur in any location Closely related…
Fibromatosis Elizabeth A. Montgomery, MD Key Facts Terminology Palmar fibromatosis: Dupuytren contracture, Dupuytren disease Plantar fibromatosis: Ledderhose disease Penile fibromatosis: Peyronie disease Deep fibromatosis: Aggressive fibromatosis, desmoid tumor Myofibroblastic proliferations…
Lipofibromatosis Elizabeth A. Montgomery, MD Key Facts Clinical Issues Painless mass Hands and feet of children Median age: 1 year Male predominance (M:F = 2:1) Local recurrences common No metastases…
Nasopharyngeal Angiofibroma Lester Thompson, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign, highly cellular, and richly vascularized mesenchymal neoplasm arising in nasopharynx in males Clinical Issues Recurrent, spontaneous…
Giant Cell Angiofibroma Amitabh Srivastava, MD Key Facts Terminology Benign fibroblastic tumor with multinucleated tumor giant cells and angiectoid spaces May be related to solitary fibrous tumor/hemangiopericytoma group Clinical Issues…
Dermatomyofibroma David S. Cassarino, MD, PhD Key Facts Terminology Myofibroblastic tumor with features overlapping with dermatofibroma Clinical Issues Slow-growing plaque or nodule Microscopic Pathology Dermal-based spindle cell proliferation Tumor is…
Fibrous Hamartoma of Infancy Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign superficial fibrous lesion occurring during 1st 2 years of life Clinical Issues Congenital in up to 25%…
Ischemic Fasciitis Elizabeth A. Montgomery, MD Key Facts Terminology Pseudosarcomatous proliferation Clinical Issues Mean age: 8th decade Most cases do not recur following excision Microscopic Pathology Most involve deep subcutis…
