Myeloid Sarcoma
Myeloid Sarcoma Definition A tumor mass of immature myeloid cells involving an extramedullary site or bone (1). The neoplasm can precede, occur concurrently, or arise subsequent to the diagnosis of…
Angioimmunoblastic T-Cell Lymphoma
Angioimmunoblastic T-Cell Lymphoma Definition Angioimmunoblastic T-cell lymphoma (AILT) is a specific type of peripheral T-cell lymphoma that is characterized by lymphadenopathy, systemic disease, and associated immunodysregulation and immunodeficiency (1). Synonyms…
Introduction
Introduction In addition to its various populations of lymphocytes, lymph nodes are composed of other cell types, including cells derived from the monocytic lineage, and cells that comprise the lymph…
Peripheral T-Cell Lymphoma, Unspecified
Peripheral T-Cell Lymphoma, Unspecified Definition Peripheral T-cell lymphomas (PTCL) are neoplasms of mature T-cell lineage that usually present with a lymphomatous clinical picture. In the World Health Organization (WHO) classification,…
Mycosis Fungoides
Mycosis Fungoides The term primary cutaneous lymphoma refers to a lymphoma initially diagnosed by skin biopsy in patients without evidence of extracutaneous disease. In the recent World Health Organization (WHO)/European…
Adult T-Cell Leukemia/Lymphoma
Adult T-Cell Leukemia/Lymphoma Definition Adult T-cell leukemia/lymphoma (ATLL) is a T-cell neoplasm caused by infection by human T-cell lymphotropic virus type 1 (HTLV-1). Four clinical variants are recognized: acute, lymphomatous,…
Mantle Cell Lymphoma
Mantle Cell Lymphoma Definition Mantle cell lymphoma (MCL) is a clinically aggressive B-cell lymphoma associated with the t(11;14)(q13;q32) and cyclin D1 overexpression in almost all cases (1). Originally, MCL was…
Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma Definition Non-Hodgkin diffuse lymphoma of large B cells. Synonyms Lymphoma, diffuse, histiocytic (Rappaport) (1); Lymphoma, large-cell, cleaved, noncleaved, and immunoblastic (Lukes-Collins) (2); Lymphoma, centroblastic and immunoblastic…
Burkitt Lymphoma
Burkitt Lymphoma Definition Burkitt lymphoma (BL) is defined in the WHO classification as a highly aggressive lymphoma, often extranodal, composed of monomorphic, medium-sized B cells with basophilic cytoplasm and numerous…
Lymphomas of Salivary Glands
Lymphomas of Salivary Glands Definition Lymphomas of the salivary glands develop in the lymph nodes and lymphoid tissues embedded in the salivary glands. Epidemiology Lymphomas developing primarily in salivary glands…
