Principles of Patient Recruitment and Retention
Principles of Patient Recruitment and Retention I will not let him stir Till I have used the approved means I have, With wholesome syrups, drugs, and holy prayers, To make…
Monitoring and Auditing a Clinical Trial
Monitoring and Auditing a Clinical Trial Neurotic means he is not as sensible as I am, and psychotic means he’s even worse than my brother-in-law. –Karl Menninger The grand aim…
Phase 4 Trials and Postapproval Pharmacovigilance Methodologies
Phase 4 Trials and Postapproval Pharmacovigilance Methodologies In science, ‘fact’ can only mean ‘confirmed to such a degree that it would be perverse to withhold provisional assent.’ I suppose that…
Groups that Influence Protocol Design
Groups that Influence Protocol Design The practice of medicine will be very much as you make it—to one a worry, a care, a perpetual annoyance; to another, a daily job…
Overview of Phase 4 and Postapproval Clinical Activities
Overview of Phase 4 and Postapproval Clinical Activities A theory is the more impressive the greater the simplicity of its premises, the more different kinds of things it relates, and…
Introduction to Clinical Trials
Introduction to Clinical Trials The history of drugs has never been a particularly attractive subject in medical education, and one reason for this is that it is so unbelievably deplorable…
Collecting and Interpreting Life Events Data in Clinical Trials
Collecting and Interpreting Life Events Data in Clinical Trials If you want to live a happy life, tie it to a goal, not to people or things. –Albert Einstein The…
Designing and Implementing a Clinical Trial
Designing and Implementing a Clinical Trial One doesn’t discover new lands without consenting to lose sight of the shore for a very long time. –Andre Gide (1869-1951). Discovery consists in…
Questions to Ask about a Clinical Trial Protocol
Questions to Ask about a Clinical Trial Protocol There are in fact two things, science and opinion; the former begets knowledge, the latter ignorance. –Hippocrates (460-377 BC). Science is organized…
Creating a Clinical Strategy and Development Plan for a New Drug or Indication
Creating a Clinical Strategy and Development Plan for a New Drug or Indication It is a good morning exercise for a research scientist to discard a pet hypothesis every day…
