Year withdrawn Drug (generic name) Reason withdrawn 1982 Clomacron Hepatotoxicity (UK) 1983 Zimeldine Hypersensitivity, Guillain-Barre syndrome (worldwide) 1986 Nomifensine Hemolytic anemia (worldwide) 1991 Triazolam Depression, amnesia (UK, France, and other…
Fig. 3.1 Dilution bias: cumulative (left) and instantaneous (right) reporting rates for death by suicide among all reports for three antidepressants in the UK. After a TV show discussed this…
Imaging modality Setting (labs vs intensive care units, interventional or operating room) Feasibility (selective criteria; renal function) Accuracy in wall evaluation and non mobile atheroma Accuracy in wall evaluation and…
Figure 6.1 DeBakey and Stanford classification of aortic dissection. The DeBakey classification system categorizes dissections based on the origin of the intimal tear and the extent of the dissection: Type…
Figure 5.1 Aortic dissection classification: DeBakey and Stanford classification as the currently most frequently used classification systems for aortic dissection Prevalence of Risk Factors Aortic dissection and its variants are…
Absence of family history Aortic root dilatationa or aortic root dissection AND ectopia lentis Aortic root dilatationa or aortic root dissection AND FBN1 mutation Aortic root dilatationa or aortic root…
Figure 3.1 Age at surgery according to the type of TAA Actually, available literature about TAA is limited, and there has been very few medical studies in this group of…
Fig. 1 Schematic diagram of origins of PAR ligands in the skin. Figure shows cross section through the skin. The proteases originate from endogenous sources including keratinocytes and immune cells…
Neuraxial opioids Treatment drug and doses Outcomes and conclusion References Intrathecal morphine 10–320 μg Intravenous nalmefene (MOP antagonist) 10–32 μg/kg Effective Scratching responses: ↓ Ko and Naughton (2000) Intrathecal morphine 32 μg Intramuscular…
