Basicmedical Key

  Positive Negative Germ cell tumors Seminoma Spermatocytic tumor Embryonal carcinomas Yolk sac tumors Choriocarcinoma Teratomas (epithelial elements) Non germ cell tumors GISTs, angiomyolipoma, mastocytosis, thymic carcinomas, lung carcinomas, etc….

Mediastinal germ cell tumor Frequency (% cases) Teratoma 43–75 Seminoma 10–37 Yolk sac tumor 2–12 Embryonal carcinoma 2–8 Choriocarcinoma 2 Mature mediastinal teratomas have been described in patients between 1…

  Proportion of population covered by cancer registries included in EUROCARE-5 (%)a Number of germ cell tumor cases registered in 2000–2007 Austria 100 2.610 Belgium (Flanders) 58 1.215 Bulgaria 100…

Fig. 11.1 Fetal type adenocarcinoma of the lung. Branching tubules lined by cylindrical epithelium with prominent vacuolation displaying morular aggregates with cells exhibiting optically clear nuclei 11.3 Stomach Gastric teratomas…

Germinoma Embryonal carcinoma Yolk sac tumor Choriocarcinoma Teratoma  Immature  Mature  With malignant transformation Mixed germ cell Other proposed classification systems separate histologic variants into different therapeutic groups based on their…

  Type I GCT Type II GCT Type III GCT Type IV GCT Frequency Rare Uncommon Rare Common Location Testis Ovary Extragonadal Testis Ovary Extragonadal Testis Ovary Preexisting GCT Prepubertal…

Age group Anatomical site Usual histologic type Comments Newborn/infancy Sacrococcygeal (40 %) Ovary mediastinal > abdominal (15–20 % vs. 5 %) Cervicofacial (rare <5 %) Teratoma GCT are the most…

Fig. 1.1 The relative incidence of testicular tumors in the study of Friedman and Moore [11] (Reproduced with permission of the publisher) Fig. 1.2 Schematic drawing illustrating the developmental potential…