Non-neoplastic Prevascular Thymic cyst True thymic hyperplasia Thymic follicular hyperplasia Thyroid goiter Parathyroid hyperplasia Fibrosing mediastinitis Castleman disease Visceral Pericardial cyst Bronchogenic cyst Paravertebral Esophageal cyst Gastric, enteric, or…
Fig. 6.1 Mature teratoma. A needle core biopsy shows skin with epidermis (a, arrow, b), and sebaceous glands. In another area (a, arrowhead, c), respiratory epithelium is present. These findings are…
© Springer International Publishing AG 2017Anja C. Roden and Andre L. Moreira (eds.)Mediastinal Lesions10.1007/978-3-319-48379-5_11 11. Summary Andre L. Moreira1 and Anja C. Roden2 (1) Department of Pathology, New York University Langone Medical Center, 560 First Avenue, New York, NY 10016,…
© Springer International Publishing AG 2017Anja C. Roden and Andre L. Moreira (eds.)Mediastinal Lesions10.1007/978-3-319-48379-5_1 1. Introduction Frank Detterbeck1 (1) Section of Thoracic Surgery, Yale Thoracic Oncology Program, School of Medicine, Yale University, New Haven, USA …
Fig. 22.1 Advancement through different phases in clinical trials Clinical trial design for oncology studies can broadly be categorized into rule-based and model-based designs. Rule-based designs are often used in…
Fig. 17.1 (a) Kaplan-Meier survival plots for baseline DCE-MRI parameters in breast cancer patients scheduled to undergo neoadjuvant chemotherapy. Left: overall survival plot for the relative signal enhancement at 30…
Fig. 16.1 A wound response signature of genes differentially expressed between tissue from reduction mammoplasty and histologically normal tissue of cancer patients. The dendrogram in cancer-adjacent normal samples (red) and…
Fig. 2.1 Phenotypic and molecular heterogeneity of endothelium at different metastatic sites. Although the endothelium is a common barrier encountered by tumor cells at all metastatic sites, tissue-specific heterogeneity means…
Fig. 21.1 Nodular malignant melanoma . Cutaneous melanoma of the nodular subtype. Please note the red halo around the lesion representing an inflammatory immune response against neo-antigens present in the…
Fig. 12.1 Mechanisms of platelet activation. Under normal, physiological conditions, platelets rapidly form a clot upon contact with a site of vascular damage (a). Damage to the endothelium leads to…
