Somatic-Type Malignancy in Germ Cell Tumors
Type I GCT Type II GCT Type III GCT Type IV GCT Frequency Rare Uncommon Rare Common Location Testis Ovary Extragonadal Testis Ovary Extragonadal Testis Ovary Preexisting GCT Prepubertal…
Pediatric Germ Cell Tumors
Age group Anatomical site Usual histologic type Comments Newborn/infancy Sacrococcygeal (40 %) Ovary mediastinal > abdominal (15–20 % vs. 5 %) Cervicofacial (rare <5 %) Teratoma GCT are the most…
Germ Cell Tumors: Classifications, Definitions, and Terminology
Fig. 1.1 The relative incidence of testicular tumors in the study of Friedman and Moore [11] (Reproduced with permission of the publisher) Fig. 1.2 Schematic drawing illustrating the developmental potential…
Management of Germ Cell Tumors
Taken from the American Cancer Society Website: http://www.cancer.org/cancer/testicularcancer/detailedguide/testicular-cancer-staging The TNM staging system A staging system is a standard way for your cancer care team to sum up the extent of…
Thymic Epithelial Tumors and Benign Thymic Lesions
Relative frequencya Age (y) range (average) Gender (male:female) Myasthenia Gravis (+)b range (mean) Masaoka stage I (%) II (%) III (%) IVa (%) IVb (%) Type A 11.5% (3.1–26.2)…
Cytologic Features of Mediastinal Lesions
Prevascular Mediastinum – Metastatic carcinoma – Thymoma and thymic carcinoma – Germ Cell Tumor – Lymphoma – Thymic cyst – Pericardial cyst – Thymic hyperplasia Visceral Mediastinum – Metastatic carcinoma…
Radiologic Features of Mediastinal Lesions
Compartment Boundaries Major contents Prevascular Superior: Thoracic inlet Inferior: Diaphragm Anterior: Sternum Lateral: Parietal (mediastinal) pleural reflections; lateral margin of the bilateral internal thoracic arteries and veins, and superior and…
NUT Carcinoma
Fig. 7.1 A CT scan shows the appearance of a NUT carcinoma, as a hypoattenuating, heterogenously enhancing, necrotic mass with poorly defined, infiltrative borders It was in this rare cancer that…
Soft Tissue Tumors of the Mediastinum
Fig. 10.1 Lipoma with mature adipose tissue and uniform-sized adipocytes (H & E, 200×) Lipoma Variants Angiolipoma is an adipocytic tumor composed of proliferation of vascular channels, mostly capillaries, in adipose…
Lymphomas of the Thymus and Mediastinum
Fig. 8.1 H&E morphology of primary mediastinal large B cell lymphoma. a+b Low power view showing solid as well as diffuse infiltrative tumor areas. b Higher magnification shows interstitial infiltration of…
