Monitoring of NADH in Human Brain and Body Organs

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Monitoring of NADH in Human Brain and Body Organs

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsNADH monitoring in patientsCardiovascular patientsPatients in neurosurgical OR and ICUNADH responses during kidney transplantation 9.1 Introduction One of the main…

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Spectroscopic Monitoring of NADH: Historical Overview

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Spectroscopic Monitoring of NADH: Historical Overview

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsDPNHPyridine nucleotidesNADH fluorescence spectraUV light absorption by NADHState 4–3 transitionIsolated mitochondriaIn vivo NADH spectrum 3.1 Introduction It is now 60…

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Monitoring of NADH Together with Other Tissue Physiological Parameters

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Monitoring of NADH Together with Other Tissue Physiological Parameters

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsMultiparametric approachMinimally invasive techniquesTissue compartmentsMicrocirculatory blood flowHemoglobin oxygenationTissue pO2 Ionic homeostasisLaser Doppler flowmetry 5.1 Introduction Evaluation of brain physiological functions,…

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Monitoring of Various Organs in Different Animal Models

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Monitoring of Various Organs in Different Animal Models

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsMonitoring of NADH in vivoMonitoring of different organsMonitoring of various animals 8.1 Introduction Since the early stages of NADH monitoring…

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Discussion and Conclusions

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Discussion and Conclusions

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsIn vivo monitoringMetabolic stateIn vivo versus in vitroVitality indexPatient monitoring In this book, I tried to provide the reader with…

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Tissue Energy Metabolism and Mitochondrial Function

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Tissue Energy Metabolism and Mitochondrial Function

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsTissue oxygen balanceEnergy demandEnergy supplyATP consumptionOxygen gradient 2.1 Tissue Energy Metabolism The functional capacity of any tissue is related to…

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Introduction

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Introduction

(1) Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel   KeywordsMitochondrial functionNADH fluorescenceIn vivo monitoringOxygen balanceMultiparametric monitoring 1.1 The Mitochondrion The understanding of mitochondrial function has been a challenge for…

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Prospective

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on Prospective

Fig. 7.1 The mechanism underlying NO-repressed autophagy. NO inhibits JNK1 phosphorylation by S-nitrosylation. Decrease of phospho-Bcl-2 and increase of Bcl-2-Beclin1 interaction disrupt Vps34-Beclin1 association. NO also inhibits IKKb phosphorylation by S-nitrosylation….

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ART for Antitumor

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on ART for Antitumor

Group A415 A476 Control 24 h 0.044 ± 0.001 0.042 ± 0.004 ART 24 h 0.145 ± 0.002* 0.110 ± 0.003** ART 48 h 0.033 ± 0.001* 0.123 ± 0.002** ART 96 h 0.049 ± 0.002* 0.131 ± 0.002** ART artemisinin. The singular asterisk (*) represents statistically significant difference from…

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ART for Antiaging

Oct 28, 2017 by in BIOCHEMISTRY Comments Off on ART for Antiaging

Metabolites Pathways and genes Up/downregulation folds CR ART H2O2 Glucose Glycolysis  Acs2 −17.28 −2.63 −3.02  Adh6 −6.18 −1.54 −3.06  Ald3 −1.49 −1.83 2.13  Eno1 −1.75 −1.38 −2.26  Pdc6 −4.88 −2.16…

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