html xmlns=”http://www.w3.org/1999/xhtml” xmlns:epub=”http://www.idpf.org/2007/ops”> 11Scale-Up and Transfer of Hard Shell Formulations across Machine Types Larry L. Augsburger and Michael Levin Introduction Scaling Up within the Same Design and Operating Principle Regulatory…
Figure 8.1The parameters studied for optimization of the formulation and process variables (18) and a representative response surface* (Q10 = percent dissolved in 10 min). (Courtesy of L. Augsburger.) *Response…
Chapter 10 TRPA1 Antagonists as Potential Therapeutics for Respiratory Diseases Jessica Tan1,2; Gerald Hunsberger2; Christopher Neipp3; M. Allen McAlexander2,* 1 Department of Biology, College of Science and Technology, Temple University, Philadelphia,…
Chapter 24 Mucolipidosis Type IV Part I Ehud Goldin* SENS Research Foundation, Mountain View, CA, USA* Corresponding author: ehud.goldin@sens.org Abstract Mucolipidosis IV is a neurodevelopmental disorder caused by mutations in the…
Chapter 13 Potential Therapeutic Applications for TRPV4 Antagonists in Lung Disease Mary I. Townsley*; James C. Parker Department of Physiology and Center for Lung Biology, University of South Alabama, Mobile, Alabama,…
Chapter 12 Small Molecule Agonists and Antagonists of TRPV4 Matthew A.J. Duncton* Renovis, Inc. (a wholly owned subsidiary of Evotec AG), South San Francisco, California, USA* Corresponding author: mattduncton@yahoo.com Abstract Transient…
Chapter 14 TRPM8 as a Target for Analgesia Rory Mitchell1,*; Susan Fleetwood-Walker1,* 1 Centre for Integrative Physiology, School of Biomedical Sciences, College of Medicine & Veterinary Medicine, University of Edinburgh, Scotland,…
Chapter 6 TRPV1 Agonist Cytotoxicity for Chronic Pain Relief From Mechanistic Understanding to Clinical Application Dorothy Cimino Brown1,2,*; Michael J. Iadarola3 1 Veterinary Clinical Investigations Center, School of Veterinary Medicine, University…
Chapter 4 TRP Gene Polymorphism and Disease Risk Ina Kraus-Stojanowic1; Ralf Baron2; Ingolf Cascorbi1,* 1 Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel, Germany2 Division of Neurological Pain Research…
Chapter 16 Activating, Inhibiting, and Highjacking TRP Channels for Relief from Itch Lindsey M. Snyder1,3,4; Huizhen Huang1,3,5; Sarah E. Ross1,2,3,4,* 1 Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA2 Department…
