Fig. 14.1 Targeting strategies for multivalent and multispecific proteins. Circles and squares represent individual binding sites that can be either identical (monospecific) or different (bispecific). Ligand can simultaneously bind: a two…
Fig. 2.1 Classification of stem cells: Depending upon the differentiation potential into different lineages, stem cells are categorized as totipotent, pluripotent, multipotent, oligopotent, and unipotent 1. Totipotent: A single cell capable…
Fig. 10.1 Jablonski diagram to illustrate the electronic changes occurring in the donor and acceptor molecules during a BRET process. The donor (D) molecule is normally in its ground state energy…
Linkers Chemical structures Therapeutic agents References Acetal Diethylstilboestrol [63] Doxorubicin [64] Ester Bortezomib [65] Doxorubicin [66] Hydrazone Cisplatin [51] Doxorubicin [49, 50, 52] Geldanamycin [67] Gemcitabine [68]…
Fig. 22.1 a TEM image of ~8 nm-sized β-NaLuF4:Gd/Yb/Tm. b In vivo imaging of a black mouse after subcutaneous injection of citric acid-modified sub-10 nm-sized β-NaLuF4:Gd3+/Yb3+/Tm3+ and citric acid-modified β-NaYF4:Yb/Tm when detected from…
Fig. 32.1 Plasmonic bubble generation and detection: a cluster of gold nanoparticles in target cell, b laser pulse (green) nucleates the vapor bubble, c bubble expands and scatters a probe laser…
Fig. 33.1 A famous example of neutrophil chemotaxis and phagocytosis. The neutrophil is seen migrating toward a bacterium as it secretes some kind of unknown chemoattractant (e.g., N-formyl peptides like fMLP)….
, here D T is the thermal diffusivity of the tissue (a constant with a typical value for most tissues of ~1.4 × 10−3 cm2/s) and t p is the laser pulse duration….
Fig. 34.1 Structure of photopolymerizable macromolecular precursors: a PEG acrylate derivatives, b polyvinyl alcohol (PVA) derivatives, c dextran methacrylate, and d hyaluronic acid derivatives 34.2.2 Photoclick Reactions for Fast Crosslinking or…
Spiral Rotational Galvo MEMS Scanner Location Distal Distal Proximal Distal Fast axis >1 kHz >1 kHz 1–5 kHz >3 kHz Slow axis NA NA <10 Hz <30 Hz Footprint <3 mm <3 mm <1 cm <1 mm Fiber (mode)…
