and Jürgen Roth2 (1) Medical University of Vienna, Vienna, Austria (2) University of Zurich, Zurich, Switzerland Autophagy: Limited Self-Digestion Macroautophagy, named autophagy, is a basic process that operates under physiological…
and Jürgen Roth2 (1) Medical University of Vienna, Vienna, Austria (2) University of Zurich, Zurich, Switzerland Mitochondria: Crista and Tubulus Types, Mitochondrial Networks, and Fission Although known since the early…
and Jürgen Roth2 (1) Medical University of Vienna, Vienna, Austria (2) University of Zurich, Zurich, Switzerland Contact Sites of Rough Endoplasmic Reticulum with Mitochondria, the Plasma Membrane, and Lipid Droplets…
(1) Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Morphologic evaluation can be approached by recognizing lineage-specific features and formulating a differential diagnosis…
Fig. 4.1 Immunostaining using direct smear when cell block is not available (example 1): smears of a squamous carcinoma do not show typical diagnostic features; the diagnosis was confirmed by…
(1) Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Fine-needle aspiration (FNA) is a safe, simple, rapid, and cost-effective procedure that allows the…
(1) Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Sample Collection and Preparation The success of an FNA procedure depends on the nature…
Fig. 5.1 Multicolor flow cytometric immunophenotyping on fine-needle aspiration sample (example 1): the histogram shows coexpression of CD19 and CD5, an important feature of mantle cell lymphoma Fig. 5.2 Multicolor…
Tumor type Cytogenetic change Fusion protein Alveolar soft part sarcoma t(X;17)(p11;q25) ASPL–TFE3 Clear cell sarcoma/melanoma of soft parts t(12;22)(q13;q12) EWS–ATF1 t(2;22)(q34;q12) EWS–CREB1 Chondrosarcoma, extraskeletal myxoid t(9;22)(q22:q12) EWS–CHN t(9;17)(q22:q11) RBP56–CHN t(9;15)(q22;q21)…
Genetic alteration PTC FTC PDCa AC FA Comment BRAF V600E mutations 45 % (classic>tall cell variant>follicular variant) 20 % 20 % >90 % BRAF mutations BRAF K601E mutations 3 %…
