Biomarkers
Gold standard Positive Negative New biomarker Positive TP FP PPV = TP/(TP + FP) Negative FN TN NPV = TN/(TN + FN) Sensitivity = TP/(TP + FN) Specificity = TN/(TN + FP) TP true positives, FP false positives, FN false negatives, TN true…
Gold standard Positive Negative New biomarker Positive TP FP PPV = TP/(TP + FP) Negative FN TN NPV = TN/(TN + FN) Sensitivity = TP/(TP + FN) Specificity = TN/(TN + FP) TP true positives, FP false positives, FN false negatives, TN true…
© Springer International Publishing Switzerland 2016Lanju Zhang (ed.)Nonclinical Statistics for Pharmaceutical and Biotechnology IndustriesStatistics for Biology and Health10.1007/978-3-319-23558-5_3 3. How To Be a Good Nonclinical Statistician Bill Pikounis1 and Luc Bijnens2 (1) Janssen Research and Development,…