Nuclear Pharmacy
Fred P. Gattas 6-1. Key Points ■ Radiopharmaceuticals are mainly used for diagnostic purposes, but can also be used for palliative and therapeutic indications. ■ Technetium Tc-99m is eluted from…
Galantamine for Alzheimer’s Disease and Alzheimer’s Disease with Cerebrovascular Disease
(1) New York, New York, USA 3.1 Introduction Despite numerous attempts to develop new classes of compounds for either the progression or symptomatic treatment of Alzheimer’s disease, there have…
Basic Theory of Pharmacology for Alzheimer’s Disease
(1) Toyonaka, Japan 1.1 From the First Report of Alzheimer’s Disease to Its Establishment as a Concept An illness, later to be named Alzheimer’s disease (AD), was first reported…
How Do We Use Symptomatic Drugs to Treat Dementia?
(1) Toyonaka, Japan 6.1 Introduction Symptomatic drugs for Alzheimer’s disease (AD) target neurotransmitters. The cholinergic nervous system is closely involved in memory and learning. The AD brain shows a…
The Practical Pharmacology of Donepezil
(1) Toyonaka, Japan 2.1 Introduction From 1976 to 1977, three British groups established the acetylcholine (ACh) hypothesis, which claims that the activity of choline acetyltransferase (ChAT), an ACh synthase,…
