Angiomyofibroblastoma
Cyril Fisher, MD, DSc, FRCPath
Key Facts
Terminology
Benign stromal tumor composed of numerous capillaries and myofibroblasts
Clinical Issues
Women of reproductive age
Arises in vulva or vagina
Often thought to represent a cyst
Local excision
No recurrent potential
Microscopic Pathology
Well demarcated
Numerous thin-walled capillaries
Alternating zones of cellularity
Variably edematous to collagenous matrix
Plump, ovoid (plasmacytoid) to spindle-shaped cells
Cells cluster around capillaries
Ancillary Tests
Typically desmin(+)
TERMINOLOGY
Abbreviations
Angiomyofibroblastoma (AMF)
Definitions
Benign stromal tumor composed of numerous capillaries and myofibroblasts
ETIOLOGY/PATHOGENESIS
Cell of Origin
Subepithelial mesenchyme of distal female genital tract
CLINICAL ISSUES
Epidemiology
Age
Typically women of reproductive ageStay updated, free articles. Join our Telegram channel
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