Immunogens

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Immunogens

Key points • Patients with atopic dermatitis are more susceptible to developing irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD). • ICD can present with phenotypic subtypes such as…

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Skin Barrier

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Skin Barrier

Key points • The four layers of the epidermis—stratum corneum, stratum granulosum, stratum spinosum, and stratum basale—are composed of keratinocytes, which undergo differentiation and mature as they become more superficial…

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Epidemiology

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Epidemiology

Key points • Atopic dermatitis is one of the most common inflammatory diseases of the skin, with both genetic and environmental etiologies. • The prevalence of atopic dermatitis is increasing…

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Atopy of the Skin

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Atopy of the Skin

Key points • Atopy of the skin is manifested as atopic dermatitis (atopic eczema). • Histologically, the atopy of the skin is characterized by epidermal and dermal infiltration predominantly by…

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Atopy Redefined

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Atopy Redefined

Key points • Although the original term atopy provides a general framework of understanding about allergic clinical conditions, this big umbrella now includes a group of patients who have heterogeneous…

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Historic Perspective

Jul 23, 2022 by in GENERAL & FAMILY MEDICINE Comments Off on Historic Perspective

Key points • From the historic perspective, atopic dermatitis has gone through several evolutionary periods of understanding and development. • From ancient times to the 18th century, medical communities started…

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