Figure 44.1 Mechanism of platelet aggregation and actions of antiplatelet drugs. A, Multiple factors—thromboxane A2 (TXA2), thrombin, collagen, platelet-activating factor (PAF), and adenosine diphosphate (ADP)—promote activation of the glycoprotein (GP) IIb/IIIa receptor….
Pure Opioid Agonists Morphine Agonist-Antagonist Opioids Pentazocine Pure Opioid Antagonists Naloxone Basic Pharmacology of the Opioids Morphine Morphine is the prototype of the strong opioid analgesics and remains the standard…
] belongs to a drug class known as polyene antibiotics, so named because their structures contain a series of conjugated double bonds. Nystatin, another antifungal drug, is in the same…
Traditional Antipsychotics Chlorpromazine (a low-potency agent) Haloperidol (a high-potency agent) Atypical Antipsychotic Clozapine Three Types of Symptoms Symptoms of schizophrenia can be divided into three groups: positive symptoms, negative symptoms,…
First-Generation Nonsteroidal Antiinflammatory Drugs (NSAIDs) Aspirin Ibuprofen Second-Generation NSAID (Selective Cyclooxygenase-2 Inhibitor) Celecoxib Drug That Lacks Antiinflammatory Actions Acetaminophen Aspirin Aspirin is a highly valuable and effective medication. The drug…
Selective Serotonin Reuptake Inhibitor Fluoxetine Serotonin-Norepinephrine Reuptake Inhibitor Venlafaxine Tricyclic Antidepressant Imipramine Monoamine Oxidase Inhibitor Phenelzine Atypical Antidepressant Bupropion Drugs Used for Depression Drugs are the primary therapy for major…
] embodies the properties that typify all muscarinic agonists and will serve as our prototype for the group. Mechanism of Action Bethanechol is a direct-acting muscarinic agonist. The drug binds…
Lithium Carbamazepine Valproic acid Treatment of Bipolar Disorder Drug Therapy Types of Drugs Employed The American Psychiatric Association (APA) and the Veterans Administration both published treatment guidelines for bipolar disorder…
Figure 45.1 Stages of red blood cell development. Development of RBCs requires the cooperative interaction of several factors: bone marrow must be healthy; erythropoietin (a stimulant of RBC maturation) must be…
Figure 64.1 The emetic response: stimuli, pathways, and receptors. CTZ, chemoreceptor trigger zone. Several types of receptors are involved in the emetic response. Important among these are receptors for serotonin, glucocorticoids, substance…
