Fig. 3.1 Intramolecular and Intermolecular forces in polymers for biomedical use Intra and Inter Polymer Molecular Interactions A correct understanding of many physical and chemical properties of polymeric materials is linked…
Polymer name Manufacturer Reason Cuprophan®, Hemophan® Membrana GmbH Loss of market share, alleged lack of biocompatibility Polycarbonate (PC) Gambro Only as flat sheet membrane available Cellulose acetate (CA) Cordis Dow…
Fig. 12.1 Stimuli of SR polymers The responses are manifested as variations in the shape, surface, solubility, degree of intermolecular association and others [17]. Particularly, the subsequent polymer structure and property…
Function Purpose Examples Binding Fixation Fractured bone fixation Adhesion Adhesion of tissue pieces Closure Suturing Tissue approximation and vascular and intestinal anastomosis Covering Wound cover Sealing Topical hemostasis and air…
Scaffold Manufacturer Polymer Coating Drug Resorption time (months) Igaki-Tamai Kyoto Medical PLLA None None 24 BVS 1.0 Abbott Vascular PLLA PDLLA Everolimus 24 BVS 1.1 Abbott Vascular PLLA PDLLA Everolimus…
Fig. 17.1 Working principle of a biosensor. The analyte is specifically recognized by the bioelement. A biochemical reaction occurs upon the event of recognition leading to the generation of a signal,…
Fig. 16.1 Sequence of events leading to thrombus formation on blood-contacting surfaces (e.g., implanted medical devices) Fig. 16.2 Simplified schematic of the coagulation cascade, where clotting is initiated by either surface contact…
Fig. 6.1 Eyeball anatomy The fibrous layer is composed of a rear opaque part, the sclera, and anterior and transparent, the cornea. The cornea is the transparent frontal window of the…
Clinical steps Etching Primer Resin Etch-and-rinse (3-steps) Phosphoric acid (30–35 %) HEMA, organic solvent (ethanol/acetone/water), proprietary monomers Hydrophilic and hydrophobic monomers (HEMA, TEGDMA, Bis-GMA, UDMA), initiators Etch and rinse (2-step) Phosphoric…
Fig. 10.1 Representation of EPR effect This occurs because of the abnormalities of tumor vasculature, namely hypervascularization, aberrant vascular architecture, extensive production of vascular permeability factors and lack of lymphatic drainage…
