BLOOD

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on BLOOD

When the hemoglobin (Hgb) falls below 4 g/dL the palmar creases lose their pink color, a hallmark of severe anemia. Shortness of breath is an underappreciated manifestation of moderate to…

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THE HEART AND CIRCULATION

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on THE HEART AND CIRCULATION

The underlying hemodynamic abnormality in heart failure is an increase in ventricular end diastolic pressure. Many descriptors have been applied to the failing heart based on the presumed underlying physiology:…

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INFECTIOUS DISEASES

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on INFECTIOUS DISEASES

When an exhaustive search for infection is negative occult malignancy is the usual cause of prolonged unidentified fevers. It should be pointed out, however, that some patients recover completely with…

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PULMONARY

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on PULMONARY

Hypoxemia has serious adverse consequences and must be treated aggressively to avoid pulmonary hypertension and right heart failure (cor pulmonale). When PaO2 falls below 60 mm Hg, significant desaturation of…

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HYPERTENSION

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on HYPERTENSION

Hypertension is the most important risk factor for stroke and congestive heart failure (CHF), and an important contributor to the risk of myocardial infarction. The cardiovascular risk imposed by high…

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COMPLICATIONS OF ALCOHOLISM

Feb 19, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on COMPLICATIONS OF ALCOHOLISM

Chronic alcoholism is associated with a high incidence of peripheral sensorimotor neuropathy; sensory changes usually predominate. Axonal degeneration, induced by alcohol or the alcohol metabolite acetaldehyde, or by nutritional deficiency,…

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