Alexander PA, He Y, Chen Y, Orban J, Bryan PN (2007) The design and characterization of two proteins with 88 % sequence identity but different structure and function. Proc Natl…
Method category Method Size Pros and cons Methods references Size-exclusion chromatography HPSEC <0.1 μm Pros: fast, high throughput Cons: limited size range, limited choice of buffers, possible matrix interactions Liu…
Narhi LO, Jiang Y, Deshpande R, Kang S, Shultz J (2010) Approaches to control protein aggregation during bulk production. In: Wang W, Roberts CJ (eds) Aggregation of therapeutic proteins. Wiley,…
–-damage formulation, where only the anisotropic elastic part is assumed to damage. The resulting coupled, highly non-linear system of equations is symmetric and can conveniently be solved by standard incremental-iterative…
Nonlinear complex dynamical system 1 Introduction Flow affects the blood vessel responses in many ways, through mechanotransduction mechanisms, or by modifying the interactions between blood-borne agonists and cell receptors, especially…
Fig. 1 Illustration of the RVE generating algorithm. Material is agglomerated randomly around existing material While the volume fraction is directly regulated, the RVE structure develops indirectly by the number…
Fig. 1 Cross-section of the stent mesh, the coating, and the arterial wall: geometrical configuration and reference system (figure not to scale) Our results demonstrate a strong coupling of the…
(1) where is a diffusion parameter dependent on the total extracellular matrix density (ECM) , are advection coefficients representing chemo- and haptotactical movement controlled by growth factor concentrations and ECM…
around the vertical axis (Y) fitting the histological data. As a result, we obtained a cochlea similar to the one presented in (Fig. 3). One of the advantages of the method…
(IFN- induction. The results showed that inflammatory signals can be detected by in vivo imaging after subcutaneous implantation of biocompatible or immune stimulatory implants. However, there were specific differences depending…
