, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
, Tsunehisa Kaku2, Toru Sugiyama3 and Steven G. Silverberg4 (1) Matsue City Hospital, Matsue, Shimane, Japan (2) Department of Health Sciences, Department of Health Sciences Graduate School of Medical Sciences, Fukuoka, Fukuoka, Japan (3)…
Fig. 6.1 Dose-dependent plasma concentrations of amisulpride in 179 schizophrenic patients treated and observed under everyday conditions. Drug concentrations are highly variable. Under recommended doses of 400–800 mg/day, many patients…
Study Characteristics PEM M-PEM SCEM Setting Primary care Secondary care Prescribers General Practitioner Specialist Design Non-interventional observational cohort Data Source Secondary use of data from existing medical records Ethics Waiver…
ADE AMP (%) (5; 1,226)a MPH (%) (16; 2,092)a ATX (%) (21; 3,127)a GUA (%) (6; 1,150)a CLO (%) (1; 154)a Irritability 7–82 1–80 2–12 6–7 8 Crying 76 2–71…
Gene Polymorphism(s) Drug/drug class Type of ADR Comment on evidence HLA–B HLA-B*1502 Carbamazepine Stevens-Johnson syndrome Recommended in Asian ancestry CYP2D6 Partially or totally inactive alleles Pimozide Arrhythmia Recommended for doses…
